Objective: To establish a public information network query system for China cord blood bank by using modern information technology, to improve the efficiency of umbilical cord blood HLA matching, to simplify the workflow of cord blood HLA matching, and to effectively utilize the public resources of cord blood in China. Method： An iterative and step-by-step approach to system construction had used for establishing this information system. This system was researched and designed based on the platform technology framework, business process and database, information exchange sharing, data security protection, subsystem functions, data management and analysis, which would realize the data of cord blood resources sharing and utilization between cord blood bank and medical institutions. Results：The main functions of the system included data collection service, HLA matching service, medical institution management, blood management of medical institutions, and blood distribution management of cord blood bank, and so on. By the end of 2018, the system had integrated all the effective data of 6 cord blood public banks and 85,644 cord blood data were connected by the internet, which had conducted trials in a number of medical institutions, and had searched and retrieved 230 matching data. Conclusion：The umbilical cord blood bank information network query system is an effective tool for clinical umbilical cord blood transplantation matching query, which has the characters of high efficient, fast and accurate.

2019 Vol. 27　(8):　982- [Abstract]（ 423 ） HTML (0 KB)  PDF  (0 KB)  ( 31 )

Objective: To investigate the intention and related factors of the second child fertility of new generation migrant worker, and to provide reference for better releasing the positive effects of “universal two children” policy. Methods: The data were extracted from dynamic monitoring survey among migrants in Hubei province which conducted in 2016. Statistical description, Chi square test and binary logistic regression model were applied to analyze influential factors of the second child fertility intention. Results: Among the 1356 new generation migrant workers with one child who aged between 19 and 36 years old in Hubei province and, only 25.5% explicitly expressed their intention to having the second child. The influencing factors of another child's fertility intention included the sex of their first child, the age of the first child and the respondents, and the respondents whether had possessed medical insurance. The heavy economic burden was the main factor for unwilling the second child. Conclusion: To encourage the second child fertility intention of new generation migrant workers, it is necessary to strengthen public services and resource supply, as well as to change the social and cultural concepts.

2019 Vol. 27　(8):　990- [Abstract]（ 414 ） HTML (0 KB)  PDF  (0 KB)  ( 28 )

Objective: To explore the preventing effect of Zishen qinggan huayu decoction combined with aspirin for preeclampsia occurrence of pregnant women. Methods: 106 pregnant women with high risk factors of pregnancy induced hypertension during less than 14 gestational weeks were selected as the subjects from August 2017 to February 2019，and were randomly divided into two groups (53 cases in each groups). The women in the experimental group were received Zishen qinggan huayu decoction combined with aspirin for preventing preeclampsia during pregnancy, while the women in the control group were given aspirin only. The TCM symptom score, the incidence of preeclampsia from 20 gestational weeks to delivery, the values of systolic blood pressure (SBP) and diastolic blood pressure (DBP), the level of 24 hour proteinuria, and pregnancy outcomes, and the rate of adverse reaction of all women in the two groups were observed. Results: In the experimental group, the incidences of mild and severe preeclampsia of women had no significant different between during 20-24 gestational weeks and during 25-28 gestational weeks (P>0.05). The incidences of mild preeclampsia and severe preeclampsia of women during 29-32 gestational weeks, 33-36 gestational weeks, and 37-40 gestational weeks in the experimental group were significant lower than those of women in the control group (P<0.05). There was no significant different in the vlues of SBP and DBP of women during 20-24 gestational weeks, 25-28 gestational weeks, and 29-32 gestational weeks between the two groups (P>0.05), but the values of SBP and DBP of women during 33-36 gestational weeks and 37-40 gestational weeks in the experimental group were significant lower than those of women in the control group (P<0.05). The 24 hour urinary protein level, and the incidences of neonatal asphyxia, placental premature and fetal growth retardation of women in the experimental group were significant lower than those of women in the control group, but the values of coagulation indexes of the women in the experimental group were significant higher (P<0.05). Conclusion: Zishen qinggan huayu decoction combined with aspirin can effectively prevent preeclampsia occurrence and improve pregnancy outcomes.

2019 Vol. 27　(8):　998- [Abstract]（ 394 ） HTML (0 KB)  PDF  (0 KB)  ( 30 )

Objective: To observe the effect of dydrogesterone combined with Gushenbaotai decoction for treating elderly pregnant women with the threatened abortion who had one child. Methods: 126 women with the threatened abortion who had one child were randomly divided into two groups (63 cases in each group). The women in group A were given low dose dydrogesterone only, and the women in group B were given dydrogesterone combined with Gushenbaotai decoction. The effects of tocolytic theraphy, immune function, adverse reactions rate, fetal development situation, and perinatal complications rate of women were compared between the two groups. Result: Compared with those of women before treatment, the levels of serum beta HCG, P and E2 of women in both groups increased significantly after treatment, and which of women in group B were significant higher than those of women in group A (P<0.05). The AcA positive rate of women in group B (0.0%) was significant lower than that (11.0%) of women in group A, but the BA positive rate of women in group B (55.6%) was significant higher than that (31.8%) of women in group A (P<0.05). The successful rate of tocolytic therapy of women in group B (95.2%) was significant higher than that (81.0%) of women in group A (P<0.05), and the remission time(31.8±5.3h) and disappearance time (78.8±8.4h) of symptoms of pregnant women in group B were significant shorter than those (37.2±5.5h and 87.2±10.3h) of women in group A (P<0.05). There were no significant different in the values of fetal NT and CRL of pregnant women during 12-14 gestational weeks between the two groups (P>0.05). Conclusion: Low dose of dydrogesterone combined with Gushenbaotai decoction can improve the effect of tocolytic therapy of pregnant women with the threatened abortion and has good safety, which can effectively improve the hormone levels by immune regulation.

2019 Vol. 27　(8):　1007- [Abstract]（ 390 ） HTML (0 KB)  PDF  (0 KB)  ( 26 )

Objective: To investigate the levels of plasma TXA2 and tPA of women with endometriosis, and to study the correlation between the levels of plasma TXA2 and tPA and their prognosis. Methods: 92 women with endometriosis were selected in the observation group from June 2017 to June 2018, and other 92 healthy women were in the control group. The women in the observation group included 32 cases with stage I endometriosis, 25 cases with stage II endometriosis, 20 cases with stage III endometriosis, and 15 cases with stage IV endometriosis according to the American Reproductive Society ARSM staging method. The levels of plasma TXA2 and tPA of all women were detected. The endometriosis fertility index (EFI) of women in the observation group was measured before treatment, and the efficacy of women in the observation group were evaluated during operation and 6 months after operation. The correlation between the levels of plasma TXA2 and tPA of women and their EFI were analyzed. Results: The level of TXA2 of women in the observation group was significant higher than that of women in the control group, but the tPA level was significant lower (P<0.05). The TXA2 level of women increased and tPA level of women disease gradually when the degree of endometriosis had increased (P<0.05). In the observation group, the total effective rate of women after operation was 87.0% (80/92), and the plasma TXA2 level of women with some effect was significant lower than that of women without effect, but the tPA level was significant higher than that of women without effectiveness (P<0.05). The plasma TXA2 level was significant negative correlation to the value of EFI (r=0.525, P<0.05), but the plasma tPA level was significantly positive correlation to the value of EFI (r=0.685, P<0.05). Conclusion: The level of plasma TXA2 of women with endometriosis has increased, and the level of plasma tPA has decreased, which both are significantly associated to the degree of endometriosis, so they may be used to predicting the prognosis of women with endometriosis after operation.

2019 Vol. 27　(8):　1015- [Abstract]（ 346 ） HTML (0 KB)  PDF  (0 KB)  ( 32 )

Objective: To explore the expressions of the serum growth hormone releasing peptide (Ghrelin) and pregnancy specific β1 glycoprotein (SP1) of pregnant women with early onset severe preeclampsia, and to study their correlations to the fetal growth restriction (FGR). Methods: 124 pregnant women with early onset severe preeclampsia were selected into the study group, and other 80 normal pregnant women were selected into the control group. The levels of serum Ghrelin and SP1 of all include women were detected by ELISA. The Pearson correlation analysis was used for studying the relationships between maternal serum Ghrelin and SP1 levels and fetal weight. The women in the study group were divided into FGR group and non FGR group, and the multivariate logistic regression analysis was used to explore the influencing factors. The receiver operating characteristic curve (ROC) was used to evaluate the diagnostic values of Ghrelin and SP1 for FGR of women with early onset severe preeclampsia. Results: 23 (18.5%) newborns were FGR. Compared to that of women in non FGR group and the control group, the level of serum Ghrelin of women in FGR group had increased significantly and the level of FGR had decreased significantly (P<0.05). The level of serum Ghrelin was significantly negative correlated to the neonatal weight (r=0.537, P<0.05), and the level of SP1 was positive correlated to the neonatal weight (r=0.452, P<0.05). Logistic multifactor analysis showed that pregnancy weight, urine protein, oligohydramnios, hypertensive disorder complicating pregnancy, and the levels of Ghrelin and SP1 were the risk factors of the occurrence of FGR. ROC curve analysis showed that the AUC of Ghrelin level for diagnosing FGR was 0.725 and the cut off value was 12.1, which sensitivity and specificity were 73.9% and 78.2%. The AUC value of SP1 level for diagnosing FGR was 0.706 and the cut off value was 86.5, which sensitivity and specificity were 78.3% and 81.2%. Conclusion: The serum Ghrelin level of the pregnant women with early onset severe preeclampsia and FGR has increased and SP1 level has decreased, which both are the independent risk factors for the occurrence of early onset severe preeclampsia and may be have some predictive value for diagnosing FGR.

2019 Vol. 27　(8):　1022- [Abstract]（ 418 ） HTML (0 KB)  PDF  (0 KB)  ( 37 )

Objective: To observe the effects of q Qianggushengxue oral solution combined with risedronate sodium tablet for treating the postmenopausal women with osteoporosis. Methods：216 postmenopausal women with osteoporosis were randomly divided into the treatment group and the control group from Jan. 2015 to May 2017.All women in the two groups were treated by basic treatment, which included calcium supplied, and proper nutrition and exercise required, and the women in the control group were treated by risedronate sodium tablets (1 table/d) for 6 months, the women in the treatment group was treated by qianggushengxue oral solution (1 bottle/d) combined risedronate sodium tablets (1 table/d) for 6 months. 6 months after treatment, the effects of women were compared between the two groups. Results:  After treatment, the bone density of lumbar, femoral neck, root and radius of women in the observation group were 946.1±94.6,940.5±90.7, 950.8±89.4, and 934.6±89.5, respectively, which were significant higher than those(901.5±90.5, 896.3±89.8, 881.4±85.6, and 894.2±90.8) of women in the control group (P<0.05). The scores of disease dimension, physiological dimension, psychological dimension, social dimension and satisfaction dimension of women in the observation group were 84.7±8.5, 78.9±7.2, 74.7±7.1, 83.5±8.8, and 89.3±8.9, respectively, which were also significant higher than those (76.9±7.9, 63.5±6.8, 63.6±6.4, 83.5±8.8, and 89.3±8.9) of women in the control group (P<0.05). And the improved degree of levels of P1NP, β CrossLaps, TRACP5b and BGP of women in the observation group were 258.3±26.1, 2.5±0.2, 3.0±0.9, and 2.5±0.2, respectively, which were significant better than those (194.7±19.8, 6.8±0.6, 3.8±0.9, and 7.1±0.6) of women in the control group (P<0.05). There were no obviously adverse actions of women were found during treatment in both groups. Conclusion：Qianggushengxue oral solution combined with risedronate sodium tablet has good clinical efficacy for treating the postmenopausal women with osteoporosis.

2019 Vol. 27　(8):　1031- [Abstract]（ 430 ） HTML (0 KB)  PDF  (0 KB)  ( 35 )

Objective: To assess the influence of umbilical cord milking (UCM) during cesarean section on premature and full term infants. Methods: 968 infants were selected and divided into observation group and control group from February 2017 to November 2017. The infants in the control group were cord clamped after born immediately, and the infants in the observation group were given UCM before cord clamped. The asphyxia rate, bilirubin level, and hemoglobin value of infants, and hemorrhage volume of women in both groups were recorded after cesarean section. Result: The asphyxia rate of infants in the observation group was significant lower than that of infants in the control group (P<0.05). In the premature infants, and the hemoglobin value of infants in the observation group were significant higher than those of infants in the control group (P<0.05). There were no significant difference in bilirubin level of infants and hemorrhage volume of women between the two groups (P>0.05). Conclusion: UCM can reduce the asphyxia rate of infants (especially for premature infants) after cesarean. And UCM can increase hemoglobin level of premature infants, but has less effect on the full term infants, which can’t increase the rate of hyperbilirubinemia of infants and hemorrhage volume of women.

2019 Vol. 27　(8):　1038- [Abstract]（ 424 ） HTML (0 KB)  PDF  (0 KB)  ( 27 )

Objective: To investigate the change of Th1/Th2 value of women with recurrent spontaneous abortion (RSA) detected by flow cytometry peripheral blood stimulation method. Methods: 310 women with RSA were included in group A, 220 women without history of spontaneous abortion were in group B, 140 pregnant women with RSA were in group C, and 102 normal pregnant women were group D. There were 19 pregnant women with missed abortion. The levels of Th1 cells (CD4+/IFNγ+) and Th2 cells (CD4+/IL 4+) of all included women were detected by flow cytometry peripheral blood stimulation method after peripheral blood PMA+Ion stimulation，and the value of Th1/Th2 was calculated. Results：The Th1 cells levels of women in group A and the group B were always in the dominant state, and the dominant had no deviation to Th2 cell, there was no significant different in the value of Th1/Th2 of women between group A and group B (P>0.05). The Th1 cells levels of women in group C and the group D were still in the dominant state, and the dominant had no deviation to Th2 cell, there was no significant different in the value of Th1/Th2 of women between group C and group D (P>0.05). The Th1 cells level of pregnant women with missed abortion was also in the dominant state, and the dominant had no deviation to Th2 cell. Conclusion：The Th1 cells level of women with RSA before or after pregnancy and of the pregnant women with missed abortion are always in the dominant state, and the dominant has never deviation to their Th2 cell.

2019 Vol. 27　(8):　1044- [Abstract]（ 346 ） HTML (0 KB)  PDF  (0 KB)  ( 39 )

Objective: To investigate the value of serum HCG (human chorionic gonadotropin), E2 (estradiol 2), P (progesterone) and CA125 (cancer-associated glycogen 125) levels of women during the first trimester pregnancy for diagnosing ectopic pregnancy or threatened abortion. Methods: The data of 160 women during the first trimester pregnancy were analyzed retrospectively, which included 48 cases with threatened abortion (threatened group), 32 cases with ectopic pregnancy (ectopic group), and 80 normal pregnant women (normal group). The serum levels of beta HCG, E2, P and CA125 of all women were detected, and their value for diagnosing ectopic pregnancy or threatened abortion was analyzed. Results: Among the three groups, the serum P, E2, and beta HCG levels of women in normal group were the highest and CA125 level was the lowest in ectopic group, but the serum P, E2, and beta HCG levels of women in ectopic group were the lowest of pregnant women and CA125 level was the highest in normal group (P<0.05). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of combinative detection of serum levels of CA125, P, E2and beta HCG for the diagnosing ectopic pregnancy were which were 90.9%, 98.4%, 96.9%, 93.8% and 97.7%, respectively, which were significant higher than those of single detection of serum CA125 level, P level, E2 level or beta HCG level (P<0.05). Conclusion: During the first trimester pregnancy, there are significant different in the levels of serum beta HCG, E2, P and CA125 between the women with threatened abortion and the women with ectopic pregnancy. The combinative detection of serum levels of CA125, P, E2 and beta HCG for differential diagnosing threatened abortion or ectopic pregnancy has higher value.

2019 Vol. 27　(8):　1051- [Abstract]（ 357 ） HTML (0 KB)  PDF  (0 KB)  ( 30 )

Objective: To compare the clinical effect of modified total laparoscopic hysterectomy (MTH) and laparoscopic assisted transvaginal hysterectomy (LATH). Methods: The data of 56 patients who underwent hysterectomy due to uterine enlargement(≥ 12 gestational weeks) caused by uterine benign diseases such as uterine fibroids were collected from June 2015 to October 2018, and the patients were divided into MTH group (16 cases) and LATH group (40 cases) according to the surgical methods. The conditions related to operation of patients in the two groups were compared. Results：There was no significant different in the operative time and postoperative exhaust time of patients between the two groups (P>0.05). The intraoperative blood loss (133.2±81.7 ml), time of stay hospital (6.2±1.1 d), time of activities leaved from the bed (17.1±4.6 h), and cost of stay hospital (10838.6±2031.3 RMB) in MTH group were significant lower than those in LATH group. The satisfaction degree of patients after treatment in MTH group was 93.8%, which was significant higher than that (65.0%) of patients in LATH group, and the overall incidence of complications of patients in MTH group was 0.0%, which was significant lower than that (22.5%) of patients in LAVH group (P<0.05). Conclusion: MTH is a safety operation with little damage to human body, which can improve the recovery of patients, so it should be widely clinical application.

2019 Vol. 27　(8):　1058- [Abstract]（ 333 ） HTML (0 KB)  PDF  (0 KB)  ( 31 )

Objective: To investigate the correlation of the expression of serum tau protein and S100 protein to the nerve injury of premature. Methods: A total of 150 premature neonates with brain injury were enrolled into the observation group between April 2015 and May 2017, and further divided into group A (51 cases with mild brain injury), group B (55 cases with moderate brain injury), and group C (44 cases with severe brain injury). Another 57 normal full term neonates were enrolled into the control group during the same period. The levels of serum tau protein and S100 protein of all neonates were detected and recorded. The neonatal behavioral neurological assessment (NBNA) scores of neonates were compared among the four groups. The relationship between serum tau protein and S100 protein levels and NBNA score was analyzed. Results: The levels of serum tau protein and S100 protein of neonates in the observation group were significant higher than those (5.58±1.48 and 0.38±0.13) of neonates in the control group. In the observation group, the levels of serum tau protein and S100 protein of neonates in group C (9.23±2.21 and 1.11±0.33) were the highest, and those (6.00±0.91 and 0.66±0.16) of neonates in group A were the lowest (P<0.05), and those of neonates in group B were 7.92±1.34 and 0.87±0.18. The NBNA scores of neonates on 7d, 14d, and 28d after birth in the observation group were 28.2±1.3, 31.4±1.7, and 33.6±3.1, respectively, which were significant lower than those (37.9±1.1, 31.4±1.7, and 39.7±3.5, respectively) of neonates in the control group (P< 0.05). The serum tau protein and S100 protein levels of neonates with brain injury were negatively correlated with their NBNA score (P<0.05), and had decreased significantly as neonates growing up (P<0.05). Conclusion: The expression levels of serum tau and S100 protein of premature infants with brain injury are significantly increased, and the levels of serum tau and S100 protein are positively correlated with nerve injury degree, which can provide evidence for diagnosing and
predicting the prognosis of brain injury of premature infants.

2019 Vol. 27　(8):　1065- [Abstract]（ 365 ） HTML (0 KB)  PDF  (0 KB)  ( 32 )

Objective: To investigate the relationship between plasma miR 340 level of women with gestational diabetes mellitus (GDM) and their insulin resistance. Methods: 116 pregnant women were selected in this study as subjects, and were divided into group A (56 cases women with GDM) and group B (60 cases without GDM)from February 2016 to December 2017. The women in group A were further divided group A1 (30 women with insulin resistance, HOMA IR≥1.66) and group A2 (26 women, HOMA IR<1.66). Real time PCR (RT-PCR) technology was used to monitoring plasma miR 340 level. The insulin resistance index (HOMA IR) was calculated by steady state effect model. The plasma miR 340 level of women in the three groups were analyzed and their correlation to HOMA IR value was evaluated. Results: The plasma miR 340 level of women in group A was 0.61±0.09, and which was significant higher than that(0.10±0.02) of women in group B. The plasma miR 340 level of women in group A1 was 0.91±0.12, and which was significant higher than that(0.25±0.06) of women in group A2 (P<0.05). The plasma miR 340 expression of women in group A1 was positively correlated to the values of FPG and HOMA IR (r=0.324, 0.503, P<0.05), but was negatively correlated to the values of FINS and HOMA IS (r= 0.136, 0.302, P<0.05). Conclusion: The expression of plasma miR 340 of women with GDM increases significantly, and it is increasing following the insulin resistance becomes severe, so it can be used as an effective indicator for diagnosis and treatment of women with GDM.

2019 Vol. 27　(8):　1073- [Abstract]（ 318 ） HTML (0 KB)  PDF  (0 KB)  ( 32 )

Objective: To observation of the efficacy and safety of four-dimensional ultrasound contrast-enhanced hysterosalpingography (4D-HyCoSy) for diagnosing tubal patency of infertility women. Methods: 80 infertility women were given tested by 4D-HyCoSy and X-ray hysterosalpingography (HSG) from August 2017 to December 2018. And the different diagnostic results of all women were confirmed by laparoscopic methylene blue (CLP). The diagnostic consistency between 4D-HyCoSy or HSG and CLP were evaluated, and the adverse reactions were recorded. Results: The sensitivity, specificity and accuracy of 4D-HyCoSy were 98.3%, 90.5% and 96.3%, respectively, and the sensitivity, specificity and accuracy of HSG were 89.8%, 95.2% and 91.3%, respectively. The Kappa value consistency between 4D-HyCoSy and CLP was 0.902, which was higher than that (0.790) between HSG and CLP. The rate of women with grade II and III pain response by 4D-HyCoSy tested was 7.5%, which was significant lower than that (23.8%) of HSG (χ2=8.012,P=0.005). The rate of genital tract bleeding (26.3%) by 4D-HyCoSy tested was significant lower than that (42.5%) by HSG tested (χ2=4.682, P=0.030). The time of genital tract bleeding by 4D-HyCoSy tested was (1.12±0.24)d, which was significantly shorter than that ［(1.79±0.37)d］ by HSG tested (t=4.193, P=0.000). Conclusion: Compared with HSG tested, 4D-HyCoSy tested for diagnosing tubal patency of infertility women has high consistent, good efficacy, and high safety with less adverse reactions.

2019 Vol. 27　(8):　1079- [Abstract]（ 372 ） HTML (0 KB)  PDF  (0 KB)  ( 29 )

Objective: To analyze the influencing factors of delivery model of pregnant women with history cesarean section, and to explore the value of prenatal examination for predicting delivery model. Methods: A retrospective analysis was conducted on 182 pregnant women with history cesarean section who had required trying vaginal delivery from February 2014 to March 2016, and they were divided into in the observation group (118 women with vaginal delivery) and in the control group (64 women with cesarean section again). The general clinical data, maternal and infant outcomes, and prenatal examination data of women in both groups were analyzed, and the value of prenatal examination for predicting delivery model was explored. Results: The rates of postpartum fever, reproductive tract infection and fetal distress of women in the observation group were significant lower than those of women in the control group (P<0.05). The time interval from last cesarean section to this pregnancy again, the degree of cervical dilatation, bishop score, the cervical length, the fetal weight measured by ultrasound, the situation of posterior horn of cervix of pregnant women with history cesarean section were related to their delivery model (P<0.05). The bishop score, cervical length, and fetal weight measured by ultrasound were the influencing factors of the delivery model of women (P<0.05). ROC curve analysis showed that bishop score, cervical length, and fetal weight measured by ultrasound of pregnant women were certain values for predicting the delivery model. When bishop score was 5.789, cervical length was 28.29mm, and fetal weight measured by ultrasound was 4.263kg, it was the critical value for trying transvaginal delivery. Conclusion: Bishop score, cervical length, and fetal weight are the influencing factors of the delivery model of pregnant women with history cesarean section, which have some values for predicting transvaginal delivery successfully, and it was worthy of clinical reference.

2019 Vol. 27　(8):　1087- [Abstract]（ 392 ） HTML (0 KB)  PDF  (0 KB)  ( 28 )

Objective: To analyze the effectiveness of pelvic floor rehabilitation technology used patients with for pelvic floor dysfunction, such as urinary incontinence, pelvic organ prolapse and sexual dysfunction. Methods: 150 patients with pelvic floor dysfunction were selected and divided in two groups from December 2015 to December 2017. The patients in the control group were received conventional treatment, and the patients in the observation group were received pelvic floor rehabilitation technology treatment except to conventional treatment. The clinical efficacy of patients was compared between the two groups. Results: The level of nitric oxide (NO), pressure test index (vaginal resting pressure, pelvic floor systolic pressure), I class of muscle fiber index (value of continuous systolic pressure and duration of continuous systolic), II class of muscle fiber index (value of rapid systolic pressure and systolic number) of women in the observation group were significant higher than those of women in the control group, but the levels of relaxin (RLX), endothelin 1 (ET-1), C reactive protein (CRP) and interleukin 6 (IL 6) of patients were significant lower than those of women in the control group (P<0.05). The rate of pelvic organ prolapsed, urinary incontinence and sexual dysfunction of women in the observation group were 5.3% (4 cases), 6.7% (5 cases) and 6.7% (5 cases), respectively, which were significant lower than those ［20.0% (15 cases), 20.0% (15 cases) and 17.3% (13 cases)］ of women in the control group (P<0.05). The degree of total satisfaction satisfied of women in the observation group (96.0%) was significant higher than that (84.0%) of women in the control group (P<0.05). Conclusion: Pelvic floor rehabilitation technology for treating patients with pelvic floor dysfunction can effectively promote the pelvic floor muscle strength recovery of patients, reduce the incidences of pelvic organ prolapsed, urinary incontinence and sexual dysfunction, and can effectively improve the satisfaction of patient.

2019 Vol. 27　(8):　1095- [Abstract]（ 379 ） HTML (0 KB)  PDF  (0 KB)  ( 34 )

Objective: To analyze the influence of single port laparoscopic surgery for treating women with benign ovarian tumor on their ovarian function recovery. Methods: The clinical data of 60 women with benign ovarian tumor from March 2015 to March 2018 were collected and divided into two groups. The women in the control group were treated by porous laparoscopic surgery, and the women in the observation group were treated by single port laparoscopic surgery. The clinical efficacy of women in the two groups was analyzed. Results: The postoperative exhaust time (13.28±1.31 h) and the hospitalization time (2.61±1.45 d) of women in the observation group were significant shorter than those of women in the control group, but the operation time (63.26±8.05min ) of women in the observation group was significant longer than that of women in the control group (P>0.05). The levels of Beta endorphin, preoperative cortisol (Cor), growth hormone (HGH), and tumor necrosis factor alpha (TNF α), and the levels of immunologic function indexes (CD3+, CD4+,  CD8+, and CD4+/CD8+)) of women in the observation group were significant better than those of women in the control group (P>0.05). There were no significant different in the intraoperative blood loss volume, and levels of estradiol (E2), follicle stimulating hormone (FSH), and luteinizing hormone (LH) of women after operation, and the situation of menstrual recovery of women 3 months after operation between the two groups (P>0.05). Conclusion: Single port laparoscopic surgery for treating women with benign ovarian tumor has less influence on the immune function and ovarian function of women.

2019 Vol. 27　(8):　1102- [Abstract]（ 325 ） HTML (0 KB)  PDF  (0 KB)  ( 28 )

Objective: To investigate the analgesia effects of nalbuphine hydrochloride injection for women after laparoscopic hysterectomy, and to study its effect on the levels of mean arterial pressure (MAP), heart rate (HR) and pulse oximetry (SpO2). Methods: Sixty women who had accepted laparoscopic hysterectomy under general anesthesia were enrolled and were divided into the study group and the control group by randomized digital table. The women in the study group were treated by nalbuphine 2.0 mg/kg, and the women in the control group were treated by sufentanil 100 μg intravenous analgesia. The changes of MAP, HR, SpO2 levels at different time points, visual analog pain score (VAS) before and after analgesia, Ramsay sedation score, and adverse reaction rate of women were compared between the two groups. Results: There were no significant different in the levels of HR, SpO2 and MAP of women before surgery and at 2h, 12h, 24h and 48h after surgery between the two groups (P<0.05). The VAS scores of women in the study group at 2h, 12h and 24h after surgery were significant lower than those of the control group (P<0.05), but those of women at 48h after surgery had no significant different between the two groups (P>0.05). Ramsay sedation score of women in the study group at 2h and 12h after surgery were significant lower than those of the control group (P<0.05), but those of women at 24h and 48h after surgery had no significant different between the two groups (P>0.05). The incidence of adverse reactions of women in the study group was 10.0%, which was significant lower than that (23.3%) of women in the control group (P<0.05). Conclusion: The analgesia effects of nalbuphine hydrochloride injection for women after laparoscopic hysterectomy is better than that of sufentanil used, which can keep hemodynamic fluctuations stable of women with less adverse reactions.

2019 Vol. 27　(8):　1108- [Abstract]（ 423 ） HTML (0 KB)  PDF  (0 KB)  ( 35 )

2019 Vol. 27　(8):　1116- [Abstract]（ 486 ） HTML (0 KB)  PDF  (0 KB)  ( 31 )