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Abstract Objective: To investigate the clinical value of three dimensional color power angiography (3D CPA) used for evaluating endometrial receptivity of women with ovulation failure. Methods: The data of 60 women who had trouble ovulating from January 2017 to April 2018 were retrospective analyzed and were divided pregnancy group and non pregnancy group. All patients were treated by ovulation induction, and were examined by three dimensional transvaginal ultrasound and 3D CPA on the HCG day. The blood flow index, vascular and blood flow index, intimal vascular index, and the situation of endometrial volume of all women were analyzed. Results: There were no significant different in the age, time of infertility, body mass index, menstruation situation, levels of E2 and P on the HCG day of women between the two groups (P>0.05). The endometrial thickness, vascular index, blood flow index, endometrial volume, and vascular and blood flow index of women in pregnancy group were 11.0±2.0 mm, 38.9%, 21.1, 5.3 cm3, and 6.2, respectively, which were significant higher than those of women in non pregnancy group (P<0.05). The area under the ROC curve of the endometrial volume was 0.71, and its Jordan index, specificity, and sensitivity were 0.42, 83.3% and 58.3%, respectively. The area under the ROC curve of the endometrial vascular and blood flow index was 0.69, and its Jordan index, specificity and sensitivity were 0.43, 60.5% and 82.6%, respectively. Conclusion: 3D CPA can predict endometrial receptivity of women with ovulation failure, which is worthy of clinical promotion.
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