-
CAO Xiaohang1，BAI Zhenggang2，GAO Caiyun1，WU Huayu1，WANG Lijin1，XU Jie1，DING Guowu1
Objective: The aim of this metaanalysis was to evaluate the effectiveness of yoga treating menopausal insomnia. Methods: The information of this literature was retrieved from several databases from database built up to August 2017, which include the Cochrane Library, PubMed, EMBASE, China Journal Full Text Database, Chinese Biomedical Literature Database and Wanfang Database. The literature screening, data extraction and quality assessment were conducted according to the inclusion and exclusion criteria, and the metaanalysis was done by Stata12.0. Results: Five randomized controlled trial (RCTs) and one nonrandomized control study were included. The result of metaanalysis showed: The efficiency of patients in yoga treating menopausal insomnia group had statistical significance higher than that of women in non intervention group ［SMD=0.21, 95%CI (0.37,0.05), z=2.52, P=0.012］, the efficiency of patients in yoga treating menopausal insomnia group had no statistical significance different when compared with that of women in other measures group［SMD=0.17,95%CI(0.76,0.41), z=0.58, P=0.56; SMD=0.18, 95%CI (0.18,0.53), z=0.98, P=0.327; SMD=0.71, 95%CI (1.46, 0.04), z=1.84, P=0.065; SMD=0.24, 95%CI (062,0.14), z=1.25, P=0.21］. Conclusion: Compared with nonintervention, yoga has some effectiveness on releasing menopausal insomnia. However, there is no significant difference between yoga with wellness education and other exercise.
2018 Vol. 26 (2): 86- [Abstract]（
530
）
HTML
(0 KB)
PDF
(0 KB)
(
87
)
-
XU Xiaoou1, ZHANG Xiaojuan2*, NIE Xiaoya2, DU Qiuhua2, ZHOU Yujing2
Objective: To investigate the knowledge and attitudes about implanon of women who experienced induced abortion, and to provide evidences for promotion and education of contraception using implant. Methods: A total of 1498 women who experienced induced abortion in outpatient of Chongqing population and family planning science and technology research institute were randomly selected and answered questionnaire by self designed. The contents of questionnaire included sociodemographic characteristics,as well as knowledge and attitudes of women about implanon. Results: Among the total of 16 items about knowledge of implanon, only 5 items were answered by equal to or over than 20.0% correctly. The total mean score of knowledge about implanon was 3.0±1.2(total 16 score). The score of knowledge about implanon had no statistical significant different among women in different professional, marital status, the economic income, educational level, and the household registration. There was significant different of mean scores among women in different age (F=58.47, P<0.001). The score of women who had heard of implanon was significant higher than that of women who never heard of implanon (4.9±0.9 vs. 2.0±1.0)(P<0.001). Multiple factors analysis had showed that age and whether had heard of implanon were related factors to the score of the knowledge about implanon (t=8.13，51.72；P <0.001). 21.0% women would like to choose implanon as one of their contraceptives. Conclusion: This study indicates that the of knowledge about implanon among women who experienced induced abortion is poor. Publicity and educations of knowledge about implanon should be strengthened for women who experienced induced abortion to understand implanon correctly and objectively. More effective and appropriate contraceptives should be provided for them to reduce repeated abortion.
2018 Vol. 26 (2): 91- [Abstract]（
1862
）
HTML
(0 KB)
PDF
(0 KB)
(
157
)
-
DENG Yuao1, LIU Xinqiong1, WANG Lin1, ZHAO Fang2
Objective: To investigate the situation of anxiety and depression among infertile women with older age in Shenzhen and to explore the associated factors that influenced on anxiety and depression. Methods: 210 infertile women (3545 years old) from the infertility clinical outpatients service of Shenzhen people's hospital were recruited in this crosssectional survey between January 2016 and December 2016. General demographic and clinical information were collected by patient interview. Situation of anxiety and depression of included infertile women was assessed by Chinese version of hospital anxiety and depression scale. Prevalence and associated protective or risk factors were analyzed by SPSS. Results: In all included infertile women, 81 (38.6%) women were screened positive for anxiety and 83(395%) had depressive symptoms. Multivariate analysis indicated that women with children ［odds ratio (OR) 0.67, 95% confidence interval (CI) 0.530.93］ and higher incomes (OR 0.72, 95% CI 0.580.94) were protective factors to anxiety. Primary infertility was associated with increased depressive symptoms (OR 1.89, 95% CI 1.192.72). Higher education level (OR 0.54, 95% CI 0.330.91) and family support (OR 0.42, 95% CI 0.290.61) were protective factors to depression. Conclusion: Anxiety and depression remain highly prevalent in infertile women with age≥35 years old in Shenzhen, so it is should be paid more attention to. Regular mental health screening for all infertile patients, social support, and psychosocial care are very important for infertile women.
2018 Vol. 26 (2): 95- [Abstract]（
404
）
HTML
(0 KB)
PDF
(0 KB)
(
83
)
-
LUO Yang1, TIAN Wenjing1, LIAO Xinyu2, LI Mengling1, SONG Xiaoyan1, GUO Ziqiu1
Objective: To understand and analyze the current situation and existed problems in equal services of reproductive health for migrant women with childbearing age, and to provide evidence for government decisionmaking. Methods: A crosssectional study and facetoface interview were adopted in this investigation. Results: (1) The results of quantitative study: a total of 1230 questionnaires were issued and 1036 valid questionnaires were collected. The rate of valid questionnaire was 84.2%. The average age of subjects was (31.5±8.1) years old, but most of their education were at junior high school and high school level, and their economical income level were generally low. 31.2% of married women and 19.4% unmarried women knew about the policy of equal reproductive health services. The rates of accessing to free contraceptives of married women and of unmarried women were 32.9% and 11.9%, respectively. The rates of married women had received a free pelvic ultrasound, test of vaginal discharge routine, breast examination, and cervical smear examination were 34.4%, 30.4%, 24.9% and 23.9%, respectively. (2) The results of qualitative study: the government system was fairly completed and committed to implement the equal reproductive health services for migrant women with childbearing age. All of migrant women with childbearing age could receive free comprehensive reproductive health services provided by the state. But the needs of reproductive health services of migrant women with childbearing age should be known further by government and their selfhealth consciousness should be strengthened. Conclusion: The current acquisition rate of free reproductive health services of migrant women with childbearing age is still low, especially for unmarried migrant women with childbearing age.
2018 Vol. 26 (2): 99- [Abstract]（
370
）
HTML
(0 KB)
PDF
(0 KB)
(
41
)
-
ZHAO Yuzhi, WANG Fang, CAI Dajun
Objective: To evaluate the effect, safety and economy of water balloon dilation compared with dinoprostone suppositories for inducing labor of fullterm pregnancy. Methods: 120 women with fullterm pregnancy were divided into study group and control group. The women in study group were treated by water balloon dilation for induced labor, and the women in control group were treated by dinoprostone suppositories for induced labor. The cervical Bishop score of women in both groups were evaluated before treatment, and at 4 hours, 12 hours and 24 hours after treatment. Delivery situation of all women and state of neonate, such as neonatal Apgar score, birth weight, rate of amniotic fluid pollution and fetal distress were all recorded. Results: The cervical Bishop scores of women in both groups after treatment were significant increased than those of women before treatment (P<0.05). There were no significant difference in the cervical Bishop score of women between the two groups at 4 hours, 12 hours and 24 hours after treatment (P>0.05). Postpartum hemorrhage volume, oxytocin dosage and vaginal delivery rate of women had no statistical significant between the two groups (P>0.05). The time of treatment to delivery and time of total labor of women in study group were significant shorter than those of women in control group (P<0.05), and the cost of treatment of women in study group was also significant lower than that of women in control group (P<0.05). There were no significant difference in neonatal Apgar score, neonatal weight, rate of amniotic fluid contamination IIIII degrees, and rate of fetal distress between the two groups (P>0.05). Conclusion: Comparing to dinoprostone suppositories for inducing labor of fullterm pregnancy, water balloon dilation has better efficacy, safety and economic.
2018 Vol. 26 (2): 103- [Abstract]（
412
）
HTML
(0 KB)
PDF
(0 KB)
(
133
)
-
ZHOU Mi, WANG Li
Objective: To investigate the clinical effect of levonorgestrel releasing intrauterine system (LNGIUS) compared to medroxyprogesterone for treating perimenopausal abnormal uterine bleeding. Methods: From August 2014 to August 2016, 88 women with perimenopausal abnormal uterine bleeding in Baoji maternal and child health care Hospital of Shaanxi province were randomly divided into observation group and control group. Women in observation group were treated by LNGIUS inserted, and women in control group were treated by medroxyprogesterone acetate. The menstrual volume, menstruation time, endometrial thickness, hemoglobin (Hb) and hematocrit (Hct) of women were compared between the two groups before treatment and in 3, 6, and 12 months after treatment. And rates of adverse reactions of women in both groups were also analyzed. Results: The menstruation volume, menstrual period, endometrial thickness of women in both groups in 3, 6, 12 months after treatment were significant decreased than those of women before treatment (P< 0.05), and value of Hb and Hct had significant increased than those of women before treatment (P< 0.05). The total effective rate of women in observation group was 97.73%, which was significant higher than that of women (84.09%) in control group (P< 0.05). There was no any serious adverse reaction in both groups. Conclusion: LNGIUS sued for treating abnormal uterine bleeding of perimenopause women has better clinical effect than that of medroxyprogesterone acetate, which is worthy of promotion.
2018 Vol. 26 (2): 107- [Abstract]（
499
）
HTML
(0 KB)
PDF
(0 KB)
(
91
)
-
GUO Jia
Objective: To explore the changes and detecting significance of serum mALB, Urea, NGAL and Cys-C of pregnant women with early renal injury because of pregnancy-induced hypertension syndrome. Methods: Eighty pregnant women with pregnancyinduced hypertension syndrome from Lanzhou maternal and child health care hospital were recruited into this study from September 2015 to August 2017, which included 27 patients with pregnancyinduced hypertension, 26 patients with mild preeclampsia, 27 patients with severe preeclampsia. At the same time, the 80 cases were also divided into normal renal function group (41 cases) and renal insufficiency group (39 cases) bade on the value of creatinine clearance. Except that, 80 normal pregnant women were included in normal control group. The levels of serum mALB, Urea, NGAL and CysC of all included women were detected. And the changes of level of mALB, Urea, NGAL and CysC were analyzed, and the relationship between level of mALB, Urea, NGAL and CysC and renal injury was also explored. Results: The levels of serum mALB, Urea, NGAL and CysC of women in observation group were significant higher than those of women in control group (P<0.05). The levels of serum mALB, Urea, NGAL and CysC of women with severe preeclampsia were significant higher than those of women with pregnancyinduced hypertension or mild preeclampsia (P <0.05). The levels of serum mALB, Urea, NGAL and CysC of women with abnormal renal function were significant higher than those of women with normal renal function (P <0.05). Conclusion: The level of serum mALB, Urea, NGAL and CysC increases with the pregnancyinduced hypertension syndrome becoming more severity. Combined detecting the levels of serum mALB, Urea, NGAL and CysC of women with pregnancyinduced hypertension are beneficial to diagnose renal injury early, and has significance for clinical treatment.
2018 Vol. 26 (2): 111- [Abstract]（
443
）
HTML
(0 KB)
PDF
(0 KB)
(
71
)
-
DONG Wenhui, JI Yanfang, LIU Kun, HAN Lili
Objective: To compare the clinical efficacy and safety of misoprostol tablets with oxytocin for inducing labor of pregnant women with scar pregnancy. Methods: A total of 144 pregnant women with cicatricial uterus pregnancy, who were suitable for vaginal trial labor, were randomly divided into three groups (48 cases in control group, misoprostol group and oxytocin group). The women in misoprostol group received vaginal misoprostol tablets, the women in oxytocin group were given intravenous infusion of oxytocin, and the women in control group were given natural childbirth. Cervical maturation, parturient duration, delivery mode, prognosis of maternal and child were compared among the three groups. Results: The first, Bishop score of pregnant women in the three groups had significant different at 4h, 8h, 12h and 24h after treatment (P <0.05), and the Bishop score of pregnant women in misoprostol group was significant higher than that of pregnant women in oxytocin group (P <0.05). The second, the labor time, total parturient duration, and rate of vaginal birth of pregnant women in three groups had significant different (P <0.05). The labor time and total parturient duration of pregnant women in misoprostol group were significant shorter than those of pregnant women in oxytocin group (P >0.05), but rate of vaginal birth of pregnant women in misoprostol group and in oxytocin group had no significant different (P >0.05). The third, the total incidence of postpartum complications of pregnant women in the three groups had statistical significant different (P <0.05), but there was no significant difference of pregnant in women incidence of postpartum complications between misoprostol group and oxytocin group (P >0.05). The fourth, the total incidence of neonatal complications had statistical significant different among the three groups (P <0.05), but there was no significant difference between misoprostol group and oxytocin group (P >0.05). Conclusion：Misoprostol tablets and oxytocin can promote the maturation of maternal cervix uteri, shorten parturient duration, and reduce the risk of cesarean delivery of pregnant women with scar uterine pregnancy. Both of misoprostol and oxytocin have a similar effect on prognosis of maternal and child, but misoprostol has better effect to promote the maturation of maternal cervix uteri and to shorten parturient duration.
2018 Vol. 26 (2): 115- [Abstract]（
1943
）
HTML
(0 KB)
PDF
(0 KB)
(
159
)
-
JIANG Yitie, SHU Shu, NIE Ying, YUE Ting, LIU Jinde
Objective: To investigate the clinical efficacy of fentanyl combined with ropivacaine for epidural anesthesia in painless labor and its influence on labor process. Methods：116 parturients were randomly divided into control group and observation group (58 cases in each group). The parturients in the two groups were all treated with epidural anesthesia, the parturients in control group were injected 0.1% ropivacaine after the puncture, and the parturients in observation group were injected a mixture of 0.5 g/ml of fentanyl and 0.1% ropivacaine. The anesthetic effect, the changes of main index of parturients, and situation of labor were compared between the two groups. Results：The anesthesia excellent rate (94.8%) of parturients in observation group was significant higher than that of parturients in control group (81%). The time of the first stage of labor (6.1±2.1h, 1.7±0.4h) of parturients in observation group was significant shorter than that of parturients in control group (7.8±2.3h, 2.4±0.6h). The time of anesthesia onset (4.3±1.2min), block time (1.8±0.9 min) and duration (5.3±1.6 min ) of parturients in observation group were significant better than those of parturients in control group (13.6±2.5 min, 24.6±2.8 min, 2.5±0.6 min, respectively) (P< 0.05). But bleeding valume of parturients in observation group (198.6±40.8ml) had no significant difference when that compared to parturients in control group (195.2±41.7ml) (P>0.05). The neonatal weight in observation group (4.25±1.64kg) had also no significant difference when compared to control group (4.18±1.59kg) (P>0.05). The incidence of neonatal asphyxia (5.2%) and the incidence of fetal distress (5.2%) in observation group were significant lower than those of parturients in control group (12.1% and 13.8%) (P < 0.05). Conclusion: Fentanyl combined with ropivacaine for epidural anesthesia in painless labor can improve the anesthetic effect and can shorten the labor process, which has good clinical significance.
2018 Vol. 26 (2): 119- [Abstract]（
401
）
HTML
(0 KB)
PDF
(0 KB)
(
54
)
-
LI Changhong, XIAO Hai, YU Xiao
Objective: To investigate the relationship between the side effects of subcutaneous implantation of progesterone and peripheral blood hormones or inflammatory factors. Methods: 105 patients underwent subcutaneous implantation of progesterone were followed up. The main side effects of subcutaneous implantation of progesterone were observed. The levels of estradiol (E2), testosterone (T), testosterone (T), Interleukin2 (IL2) and tumor necrosis factor alpha (TNFα) were detected before and after implanted. Results: The main side effects were changes of vaginal bleeding pattern and facial acne. In the first 90 days and the second 90 days, peripheral blood E2 of patients with different bleeding patterns had significantly reduced (P<0.05), T, IL2 And TNFα had significantly increased(P <0.05). Conclusion: Changes of vaginal bleeding patterns and facial acne are primary side effects of progesterone subcutaneous implantation, which effects the use of progesterone subcutaneous implantation continually. So the preoperative counseling service should be strengthened, and the compliance of women's use should be improved. Relevant mechanism research should be conducted for reducing the occurrence of side reaction and developing an effective treatment.
2018 Vol. 26 (2): 122- [Abstract]（
439
）
HTML
(0 KB)
PDF
(0 KB)
(
85
)
-
XIA Yali
Objective: To investigate high risk HPV infection situation and level of T cells subgroup in peripheral blood of middle or late pregnant women with cervical intraepithelial neoplasia (CIN). Methods: From June 2014 to June 2016, 126 middle or late pregnant women with CIN who had come to Xianyang hospital affiliated to Yan 'an university for treatment were recruited into observation group, and 131 middle or late pregnant women without CIN were in control group. The positive rate of different type of highrisk HPV, rate of highrisk HPV negative conversion, DNA load of HPV and function of immune cell of all women were detected. Results: The rates of highrisk HPV infected pregnant women in observation group were HPV16 (78.57%), HPV18 (32.5%), HPV31 (8.7%), HPV33 (206%) and HPV58 (2.4%). In control group, the rates of highrisk HPV infected pregnant women were HPV16 (16.3%) and HPV31 (5.3%). The positive rate of HPV16, HPV18 and HPV33 of women in observation group were significant higher than those of women in control group (P<0.05). Compared to those of women in control group at six months after labor, in observation group, with increasing degree of CIN of women, highrisk HPV infection positive rate increased, the positive rate of high risk HPV infected increased, and rate of high risk HPV nature negative conversion decreased, DNA load of high risk HPV increased, which had all statistically significant different (P<0.05). In observation group, the number of CD4、CD4/CD8 of women with different CIN stage had statistically significant different before labor (F=3.299,3.207, P<0.05), and number of CD4 of women with different CIN stage had statistically significant different after six months postpartum (F=13.11, P<0.001). Conclusion: DNA load of highrisk HPV and level of T lymphocyte subsets of middle or late pregnant women with CIN detected early can help for diagnosis and prognosis monitoring of highrisk HPV infected in middle and late pregnant women. Improving cellular immune function can inhibit HPV infected.
2018 Vol. 26 (2): 126- [Abstract]（
451
）
HTML
(0 KB)
PDF
(0 KB)
(
68
)
-
ZHANG Juanjuan1, CHEN Yinghong2, WANG Changfu3
Objective: To investigate the value of ultrasound(US) and magnetic resonance imaging( MRI) in diagnosis of cesarean scar pregnancy(CSP), and to explore the feasibility of US combined with MRI to improve the value for diagnosing cesarean scar pregnancy. Methods：Data of 68 patients who were initially diagnosed as CSP were collected. The sensitivity, specificity and accuracy of US, MRI, US combined with MRI were compared. The diagnostic gold standard was pathology. Results：56 patients were confirmed as CSP and 12 patients were confirmed as intrauterine pregnancy by postoperative pathology in the all 68 patients, while 48 patients were diagnosed CSP by US, and 50 patients were diagnosed CSP by MRI, and 55 patients were diagnosed CSP by US combined with MRI. The sensitivity of the three method was 85.71％, 83.88％, 85.29％, respectively. The specificity of the three method was 89.29％, 7500％, 86.76％, respectively. And the accuracy of the three method was 96.43％, 83.33％, 94.12％, respectively. There was no statistical significant difference in the accuracy among three methods(P=0.049), US compared to MRI(P=0.085,＞0.05) and MRI compared to US combined with MRI(P=0.028,＞0.017) had no statistical significant difference, but US compared to US combined with MRI hadstatistical significant difference (P=0.016＜0.017). In 56 CSP patients, gestational sac was found in 40 patients and solid mass was found in 16 patients by pathology. Among them, 39 gestational sac and 9 solid mass were diagnosed by US, 34 gestational sac and 16 solid mass were diagnosed by MRI, and 39 gestational sac and 16 solid mass were diagnosed by US combined with MRI. There was statistical significant difference in diagnosing gestational sac and solid mass between US and MRI (P=0.035, P=0.003). Conclusion：The coincidence rate in diagnosis of CSP by US or MRI is higher. US is superior to MRI for diagnosing gestational sac, while MRI is better than US for diagnosing solid mass. US combined with MRI has more value in early diagnosis of CSP and can reduce misdiagnosis rate.
2018 Vol. 26 (2): 130- [Abstract]（
502
）
HTML
(0 KB)
PDF
(0 KB)
(
52
)
-
LI Yadong1,2，Zhang Shucheng2，Gu Yiqun2
Iodine is one of the essential elements of human, which plays a role and regulates the processes of thyroid hormone metabolism, and is critical for maintaining physical process and reproductive function. Spermatogenesis of male are affected by not only genetic and endocrine factors, but also are influenced by environmental factors. In fact, environmental factors are more important than body own factors. So, it is a hot spot for knowing and identifying the specific environmental factors effected on male spermatogenesis in andrology. Taking a further look at idoine, especially knowing whether intaking excess iodine will be crutial for the normal semen parameters is very important, which can ensure normal semen parameters. In order to expecting a new view on iodine played on male spermatogenesis, this article analyzes the mechanism of idoine on male spermatogenesis, and clarifies the relationship of idoine effects on testis tissue by influencing thyroid hormone.
2018 Vol. 26 (2): 147- [Abstract]（
466
）
HTML
(0 KB)
PDF
(0 KB)
(
85
)
