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• 2012 Volume 20 Issue 8
  Published: 15 August 2012

    

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  Effects of medical abortion and surgical abortion on psychological situation among unmarried women

  Chu Guanghua, Cong Jie, Wang Kun, Zou Yan

  2012, 20(8): 518. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To explore the effects of medical abortion and surgical abortion on the psychological situation among unmarried women. Methods: Eight medical databases (MEDLINE, EMBASE, Cochrane Library, CMCC/CMAC, CBM, CNKI, VIP and Wanfang) and 12 relative journals were searched. References of included studies were reviewed additionally. Two qualified reviewers reviewed original articles, evaluated qualities of articles, and extracted data independently. After a heterogeneity test, data were pooled using Revman software or underwent descriptive analysis. Results: There were significant differences in SCL-90 somatization score, SCL-90 total score, the general symptomatic index, the positive symptom distress level, the number of positive items between medical abortion group and surgical abortion group (P all <0.05). There were no significant differences in other indicators between the two groups. Conclusion: In comparison with surgical abortion, medical abortion has less harmful effects on the psychological situation of unmarried women.
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  Knowledge and awareness of oral contraceptives among family planning providers of township level

  Jiang Lifang, Li He, Zhang Junxi, Qiao Yuhui

  2012, 20(8): 522. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To understand the knowledge and awareness of oral contraceptives, and to explore the influencing factors among the family planning providers of township level in Henan Province. Methods: A total of 180 family planning providers of township level selected by a simple random sampling and interviewed with a self-designed questionnaire, which included basic characteristics, relative knowledge and awareness of oral contraceptives and training received and so on. Data were analyzed by SPSS13.0 software. Results: Respondents considered that Levonorgestrel Tablets (22.07%), Norethisterone Compound (17.93%), and Compound Levonorgestrel Triphasic Tablets (14.48%) had good contraceptive efficacy. About 63.22% of respondents considered that side effects of contraceptives could be acceptable. The main impact factors of oral contraceptive use included rejection of this method (57.74%), lack of awareness of this method (49.41%), considering it having an influence upon reproduction (17.26%). Evaluation results of the knowledge of oral contraceptives showed that 23 persons (13.69%) got a score of zero, 112 (66.7%) got less than 60 and 33 (19.6%) scored more than 60. Univariate analysis showed that professional title, the number of training on contraceptives undergone, the number of family planning providers who went countryside for publicity and education on contraceptive knowledge and training needs had significant impact on knowledge scores (P<0.05). Multiple logistic regression analysis showed that professional title, the number of training on contraceptives undergone were main factors. Conclusion: Family planning providers of township level lack of the knowledge and awareness of oral contraceptives, which is influenced by their professional titles and training undergone.
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  Desire for contraceptive use in women with recurrent induced abortion in Beijing

  Shen Jie, Gao Lili, Zhang Songwen, Pan Ying

  2012, 20(8): 525. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To explore the desire for contraceptive use and its influencing factors among women who experienced recurrent induced abortion in Beijing. Methods: Stratified cluster sampling was conducted. Women undergoing an induced abortion between Jan.2005 and Sep.2010 and recurrent induced abortion between Jan.2010 and Oct.2011 were recruited. Randomized data collected with a questionnaire survey in various areas in Beijing and analysed with Chi-squared test and logistic regression. Results: About 56.4% of respondents experienced induced abortion at least 2 times. And this time, 90.47% unwanted pregnancy was found, and 12.44% were not going to use contraceptives. For those who wanted to use contraceptives, 80.0% wanted to use condom or oral contraceptives, while 6.83% wanted to use rhythm method or withdrawal. The logistic regression result showed that husband (sexual partner) involvement(OR=2.078, P=0.033)and post-abortion care provided by service providers (OR=4.492, P<0.01) could be helpful for contraceptive use after recurrent induced abortion. Conclusion: The normative post-abortion care and promotion of male involvement in contraception are important for contraceptive use after induced abortion.
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  Factors influencing the utilization of preconception care services

  Liu Song, Yu Zhenjie, Liu Xiangyu, Li Xiangyun, Huang Dongmei, Wang Panli

  2012, 20(8): 528. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To explore status of preconception care services and its influencing factors. Methods: Random sampling was conducted among women who gave live birth between July and September 2009 in three provinces, Shandong, Henan and Gansu. A self-designed questionnaire was used and influencing factors were evaluated with a statistical method. Results: Multivariate logistic regression analysis results showed that main influencing factors included age, nationality, residence place, education level and the attitude to the examination of preconception health. Conclusion: Health education, the improvement of medical conditions and a safe, standard and personalized preconception health examination service should be promoted.
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  Prevalence of birth defects and related risk factors among children age 0-3 years old in Yuhang District

  Wang Qiaoqiao, Zhou Renjing, Chen Qinfang, Liu Xiaoqin, Yuan Wei, Wang Bo

  2012, 20(8): 531. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To know about the prevalence of birth defects in Yuhang District of Hangzhou City and to explore the risk factors related to birth defects. Methods: A total of 21 713 children aged 0-3 years old were investigated in Yuhang District. A case-control study was used to determine potential risk factors. Results: A total of 365 children with birth defects were found. Low income, poor health during pregnancy, strenuous work for women three months before pregnancy and taking medicine during pregnancy could increase the risk of birth defects. Moreover, experience of second-smoking exposure for pregnant women, spouses' poor health status and elder age (above 35 years old) also contributed to birth defects. Conclusion: It is necessary to prevent birth defects by improving the knowledge about health care among pregnant women and providing primary prevention strategy.
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  Levels of anti-osteopontin and anti-transferrin antibodies in sera of patients with endometriosis

  Zhou Qunfang, Leng Jinhua

  2012, 20(8): 535. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To explore the pathogenesis of endometriosis by evaluating levels of anti-osteopontin and anti-transferrin antibodies in sera. Methods: The enzyme-linked immunosorbent assay was used to detect levels of anti-osteopontin and anti-transferrin antibodies in sera of 108 women with endometriosis and 88 healthy women (the control). Results: The average OD values of anti-osteopontin antibody in sera of women with endometriosis and the control were 0.84±0.25 and 0.63±0.20, respectively. The average OD values of anti-transferrin antibody in sera of women with endometriosis and the control were 1.06±0.31 and 0.75±0.27, respectively. The level of anti-osteopontin antibody in sera of women with stage I and stage II endometriosis (1.04±0.30) was significantly higher than those of women with stage III and stage IV endometriosis (0.68±0.20) and the control (0.63±0.20, P all<0.05). The positive rates of anti-osteopontin, anti-transferrin antibodies and both were 25.0% (27/108), 20.3% (22/108) and 13.9% (15/108), significantly higher than that of the control (P all<0.05). The positive correlation between anti-osteopontin antibody level and anti-transferrin antibody level was found. Conclusion: Anti-osteopontin antibody may be involved in the development of endometriosis.
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  Value of decidua basalis and uterine spiral artery blood flow on the outcome of medical abortion

  Yang Lihua, Yu Yun, Liu Juyan

  2012, 20(8): 538. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To explore the predicted value of detecting the decidua basalis and uterine spiral artery blood flow with transrectal ultrasound on the outcome of medical abortion. Methods: A retrospective analysis was conducted on 30 women with complete and incomplete abortion. The type of decidua basalis blood flow, resistance index (RI) and uterine spiral artery blood flow indexes before medical abortion, on the right day of abortion and 15 days after abortion were evaluated. Results: The type I decidua basalis blood flow signal and RI in the complete abortion group were significantly higher than those in the incomplete abortion group. While the type III blood flow signal was significantly lower in the complete abortion group (P<0.05), and there was no significant difference in the type II blood flow signal between the two groups (P>0.05). There were no significant differences in all indexes between the right day of abortion and 15 days after abortion. Conclusion: The detection of the decidua basalis and uterine spiral artery blood flow with transrectal ultrasound on the right day of abortion could predict the outcome of medical abortion.
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  Pretreatment effects of oral contraceptive pill and estrogen on the outcome of in vitro fertilization-embryo transfer in poor responders

  Xie Guangmei, Fen Fan, Ni Yali

  2012, 20(8): 541. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To compare pretreatment effects of oral contraceptive pills, oral contraceptive pills followed by estrogen and estrogen alone on the outcome of in vitro fertilization-embryo transfer(IVF-ET) in poor responders. Methods: Women in group A were administered with Marvelon daily from day 3 of menstrual cycle for 21 days. Women in group B were administered with Marvelon daily from day 3 of menstrual cycle for 21 days, followed by 2mg of estrogen daily. Women in group C were administered with 4mg of estrogen daily from middle luteal phase. Ovarian stimulation began on day 3 with a short protocol. Indicators relevant to IVF-ET were evaluated. Results: All pretreatment proposals reduced the level of basal follicle stimulating hormone to less than 10 U/L on the first day of ovarian stimulation. There were no significant differences in serum estrodiol concentration on day 3 and the day of human chorionic gonadotropin(HCG) administration between three groups (P>0.05). The endometrium thickness of women in group C was significantly higher than those of group A and group B on the day of HCG administration . The rate of cycle cancellation in group A was the highest. Women in group C resulted in the shortest Gn time and the highest pregnancy rate (P all <0.05). There were no significant differences in the number of retrieved oocytes, the number of MII oocytes and the number of embryos. Conclusion: For poor responders, pretreatment with oral contraceptives followed by 4mg of estrogen daily from the middle luteal phase prior to IVF-ET cycle could be an optimal protocol.
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  Synthesis of sperm antigen peptides and its application in detection of antisperm-antibodies

  Bai Ling, Xie Qi, She Shangyang, Xia Hongwei, Liu Yongming

  2012, 20(8): 544. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To synthesize sperm peptides for establishment of the enzyme-linked immunosorbent assay (ELISA) to detect antisperm-antibodies (AsAb) . Methods: The sperm peptide P10G, YLPl2 and SP17 were synthesized by the PS3 automated solid phase peptide synthesizer, purified by RP-HPLC and identified by mass spectrum (MS). With the synthetic peptide as a coating antigen, the ELISA method was used to detect serum concentration of AsAb. Results: The molecular weights of three synthesize peptides identified by MS were in good agreement with calculated molecular weights. The purity of the synthetic peptides purified by HPLC was 97.5%, 97.78% and 95.5%. AsAb was detected by the indirect ELISA based on the peptide compared with the commercial kit, and results showed that both assays were unanimous with Kappa value more than 0.75. Conclusion: Automated solid-phase peptide synthesis could be used to synthesize high purity sperm antigen peptides. The synthesized peptide P10G, YLPl2 and SP17 show high antigenic activities and can be used as a coating antigen for indirect ELISA to detect AsAb.
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  Application of microcolumn gel technology in diagnosing hemolytic disease of the newborn

  Wang Ping, Xiao Jun, Wei Honglu

  2012, 20(8): 548. https://doi.org/10.3969/j.issn.1004-8189.2012.08

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  Objective: To explore the value of the microcolumn gel technology in diagnosing hemolytic disease of the newborn. Methods: The direct antiglobulin test (DAT), indirect antiglobulin test (IAT) and elution test were conducted with the microcolumn gel technology and the traditional method in 128 newborns suspected hemolytic disease of the newborn. Results: In 104 newborns with clinical diagnosis of hemolytic disease of the newborn, the positive rates of the microcolumn gel technology and the traditional method were 92.31% and 80.77% (χ²=5.92,P<0.05). As for three methods with the microcolumn gel technology, the positive rate of the elution test was the highest and that of DAT was the lowest. Conclusion: A microcolumn gel technology is better for assistant diagnosis of hemolytic disease of the newborn when compared with the traditional method.
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  Shifting from prenatal care to preconception care in intervention model of birth defect

  Wang Yuanyuan, Ma Xu

  2012, 20(8): 573.

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