To analyze the influence of the clinical nursing measures based on continuous quality improvement for pregnant women with severe preeclampsia (SPE) on pregnancy outcomes. Methods: A total of 120 pregnant women with SPE were randomly selected as the research objects by random sampling from January 2020 to December 2022. The enrolled women were divided into control group and observation group by random number table method, with 60 cases in each group. The women in the control group were given routine nursing intervention, and the women in the observation group were given clinical nursing measures based on continuous quality improvement. The gestational weeks at delivery, the mode of delivery, the blood pressure value, the incidence of maternal complications and the neonatal status of the women were analyzed and compared between the two groups. Results: There was no significant difference in the mode of delivery of the women after nursing intervention between the two groups (P>0.05). The gestational weeks at delivery (37.8±2.8 weeks) of the women in the observation group was significantly higher than that (36.1±2.9 weeks) of the women in the control group (P<0.05). The values of systolic and diastolic blood pressure of the women in the two groups had decreased significantly, and which(126.8±14.0 mmHg and 88.5±6.8 mmHg) of the women in the observation group were significantly lower than those(135.5±13.4 mmHg and 92.5±6.3 mmHg) of the women in the control group. The incidence of maternal complications (6.7%) and the incidence of neonatal complications (11.7%) in the observation group were significantly lower than those (20.2% and 26.7%) in the control group. The neonatal Apgar score (7.8±1.0 points) in the observation group was significantly higher than that (7.1±1.3 points) in the control group(all P<0.05). Conclusion: The clinical nursing measures based on continuous quality improvement for the pregnant women with SPE can decrease their blood pressure and improve their pregnancy outcomes.