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| Value of the levels of progesterone and serumβ-human chorionic gonadotropin combined with the ultrasound examination for diagnosing the early ectopic pregnancy |
| The Sixth People's Hospital of Chengdu, Sichuan Province, 610058 |
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Abstract To explore the values of the levels of progesterone and serumβ-human chorionic gonadotropin (β-HCG) combined with the ultrasound examination for diagnosing the early ectopic pregnancy. Methods: The clinical data of 200 women with suspected ectopic pregnancy from January 2020 to January 2023 were selected in this study. Among them, 100 women with ectopic pregnancy confirmed by pathological examination or surgery were included in the observation group, and 100 normal pregnant women were included in the control group. All the women were examined by ultrasound and their serum β-HCG and progesterone levels were detected. The diagnostic value of the progesterone and β-HCG levels of the women for their ectopic pregnancy was analyzed by receiver operator characteristic (ROC) curve. The diagnostic value of the progesterone and β-HCG levels combined with the ultrasound examination of the women for their ectopic pregnancy was analyzed by four grid tables. Results: The serum P and β-HCG levels of the women in the observation group were significantly lower than those of the women in the control group (P＜0.05). The ROC area under curve (AUC) of the serum P level and the β-HCG level of the women for diagnosing their ectopic pregnancy were 0.817 and 0.869. The positive rate of the ultrasound examination of the women for diagnosing their ectopic pregnancy was 74.0%. The sensitivity, the specificity, and the accuracy of the serum P and β-HCG levels combined with the ultrasonic examination of the women for diagnosing their ectopic pregnancy were 98.0%, 77.0%, and 87.5%, respectively. The diagnostic efficacy of the serum P and β-HCG levels combined with ultrasonic examination was significantly higher than that of the serum P level, the β-HCG level, and the ultrasonic examination alone. Conclusion: The levels of progesterone and serum β-HCG of the women with ectopic pregnancy decrease, which has certain diagnostic value for their ectopic pregnancy. The combination of the ultrasound examination and the levels of progesterone and serum β-HCG of the women can obviously improve the diagnostic value for their ectopic pregnancy.
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