To study the values of the combined multiple indexes levels for diagnosing ectopic pregnancy of women. Methods: The data of 60 women with ectopic pregnancy were selected in study group, and 120 normal pregnant women were selected in control group from January 2021 to January 2022. The levels of serum human chorionic gonadotropin (β-hCG), progesterone (P), microprotein miR-200c, and carbohydrate antigen 125 (CA125), and the positive results by ultrasound of the women were compared between the two groups. The diagnostic efficacy of the combined levels of serumβ-hCG, P, microprotein miR-200c, and CA125, and the positive results by ultrasound of the women for their ectopic pregnancy was analyzed. Results: The levels of P (23.69±8.29μg/L), β-hCG (9263.68±2323.68IU/L), CA125 (51.26±12.37mU/L), and ultrasonic positive detection rate (92.5%)of the women in the control group were significantly higher than those (12.59±3.96μg/L, 5659.24±1782.34IU/L, 35.26±11.24mU/L, and 86.7%)of the women in the study group, while the miR-200c level (1.36±0.38)of the women in the control group was significantly lower than that (1.83±0.36)of the women in the study group (all P＜0.001). Four kinds of combined predicted values of the women for their ectopic pregnancy were obtained by bivariate logisitc regression, which including the levels of P,β-hCG, and CA125 as predicted value 1, the levels of P,β-hCG, CA125, and miR-200c as predicted value 2, the levels of P, β-hCG, CA125, and miR-200c, combined with the results by ultrasound as predicted value 3, and the levels of P, β-hCG, and CA125, and combined with the results by ultrasound as the predicted value 4, respectively. The predictive efficacy of the four predicted values of the women for their ectopic pregnancy in the control group were significantly lower than those of the women in the study group (P＜0.001). The area under the curve (AUC)of the levels of P, β-hCG, CA125, and miR-200c, and the results by ultrasound for diagnosing their ectopic pregnancy were valuable, and which had no significantly different. The sensitivity of the predicted value 4, predicted value 3, ultrasonic results, predicted value 2, predicted value 1, P level, β-hCG level, and CA125 level of the women for their ectopic pregnancy had decreased gradually (P=0.030), and the specificity of which had no significantly different. Conclusion: Transvaginal ultrasound results, and serum miR- 200c and CA125 levels of the women all have the diagnostic value for their ectopic pregnancy, but the sensitivity of the combinations of which is increased. The indexes for diagnosing the ectopic pregnancy of the women should be selected by medical institutions according to the existing conditions.