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| Analysis of semen quality of infertile male patients with different serum apolipoprotein A1 and B levels |
| 1. School of Chemistry and Materials Science, Hebei Normal University, Shijiazhuang, Hebei Province, 050024; 2. Graduate School of Hebei Medical University;3. Hebei Research Institute for Family Planning Science and Technology (NHC Key Laboratory of Family Planning and Healthy, Hebei Key Laboratory of Reproductive Medicine) |
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Abstract To investigate the relationship between the levels of serum apolipoprotein A1 (ApoA1) and apolipoproteinB (ApoB), and the value of ApoB/ApoA1 of infertility male patients and their semen quality. Methods: A total of 889 infertile male patients were selected to detect their semen parameters and their serum ApoA1 and ApoB levels, and their ApoB/ApoA1 value was calculated. The relationship between the semen parameters of the patients and their ApoA1 and ApoB levels, and value of ApoB/ApoA1 was analyzed. Results: After grouping by the quartile method of ApoA1 level, the density and total number of sperm of the patients in group Q1 (patients with ApoA1 level <1.19g/L) was the highest, while which of the patients in group Q2 (patients with 1.19g/L≤ApoA1level <1.29g/L) was the lowest (P＜0.05). After grouping by the quartile method of ApoB level, the density and total number of sperm of the patients in group Q2 (patients with 0.78≤ApoB<0.87g/L) were significantly higher than those of the patients in the other three groups (P＜0.05). Based on the clinical criteria of the ApoA1 and ApoB levels and the value of ApoB/ApoA1 of these patients, the total sperm number of the patients with normal ApoB1 level (1.05-1.75g/L) was significantly higher than that of the patients with abnormal ApoB1 level (P＜0.05), and the total sperm number of the patients with ApoB/ApoA1﹤1 was significantly higher than that of the patients with ApoB/ApoA1≥1 (P＜0.05). Conclusion: Spermatogenesis of the infertility male patients maybe correlated with their serum ApoB and ApoB/ApoA1 levels.
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