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| Value of transvaginal ultrasound combined with serum human chorionic gonadotropin and progesterone levels of women for predicting their early ectopic pregnancy |
| Chengdu Women and Children's Center Hospital, Sichuan Province, 610091; Chendu women's and children's Center Hospital, School of medicone university of Electronc Sconence and Technology of china |
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Abstract To investigate the value of transvaginal ultrasound combined with serum human chorionic gonadotropin (hCG) and progesterone (P) levels of women for predicting their early ectopic pregnancy. Methods: The clinical data of 94 pregnant women with suspected early ectopic pregnancy from June 2017 to June 2019 were analyzed retrospectively. The gold standard for diagnosing ectopic pregnancy was based on diagnostic curettage or pathological examination results. These women had all accepted transvaginal ultrasound examination, and serum HCG and P levels detected. ROC curve was used to evaluate the value of transvaginal ultrasound combined with serum HCG and P levels for predicting early ectopic pregnancy. Results: The endometrial thickness (7.36±1.49 mm) of the women with ectopic pregnancy was significant lower than that (11.19±2.51 mm) of normal pregnant women, and the resistance index (0.74±0.18) of the women with ectopic pregnancy was significant higher than that (0.50±0.12) of normal pregnant women. The serum levels of HCG (1655.38±251.36 U/L) and P (20.54±6.88 ng/ml) of the women with ectopic pregnancy were significant lower than those (3154.67±400.39 U/L and 62.39±12.47 ng/ml) of normal pregnant women (all P＜0.05). ROC curve analysis showed that the highest AUC, the specificity, the sensitivity and the accuracy of transvaginal ultrasound combined with serum hCG and P levels of women for predicting their early ectopic pregnancy were 0.937, 95.7%, 91.7%, and 94.7%, respectively. Conclusion: Transvaginal ultrasound combined with serum hCG and P levels of women for predicting their early ectopic pregnancy has higher clinical value, which can provide evidences for clinical early finding, diagnosis and treatment of ectopic pregnancy.
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