Abstract To explore the effect of Qingre Liniao Tonglin recipe for treating patients with non gonococcal urethritis, and to study its influence on the related factors. Methods: 200 patients with non gonococcal urethritis were selected and were randomly divided into two groups (100 cases in each group). The patients in the two groups were all given western medicine antibiotics, and patients in the experimental group were given Chinese medicine Qingre Liniao Tongling recipe for 2 weeks additionally. The clinical symptom scores, and the levels of serum IL-2, IL-4 and IL-8 before and after treatment, and the clinical efficacy of patients were compared between the two groups. Results: After treatment, the rates of urinary frequency, dysuria, urinary urgency, urinary tract pruritus, and urethral secretion, and the score of yellow and red of urine of patients in the experimental group were significant lower than those of patients in the control group. After treatment, the serum IL-2, IL-4 and IL-8 levels of patients in the experimental group were 103.2±11.0 ng/L, 128.5±26.4 ng/L, and 75.1±16.3 ng/L, respectively, which were significant lower than those (114.2±13.5 ng/L, 143.2±28.1 ng/L, and 86.6±18.5 ng/L, respectively) of patients in the control group, but the total clinical efficacy of the patients in the experimental group was 95.8%, which was significant lower than that (92.9%) of patients in the control group (all P＜0.05). Conclusion: The effect of Chinese medicine Qingre Liniao Tonglin recipe combined with Western medicine for treating patients with non gonococcal urethritis is better than that of Western medicine used only, which can reduce the levels of inflammatory factor of patients.
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