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| The influence of pentazocine maintenance anesthesia on the postoperative analgesia and sex hormone levels of patients after laparoscopic surgery under general anesthesia |
| Shuangliu District Maternal and Child Health Care Hospital of Chengdu, Sichuan Province, 610200 |
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Abstract To investigate the influence of pentazocine maintenance anesthesia on the postoperative analgesia and sex hormone levels of patients after laparoscopic surgery under general anesthesia. Methods: 104 patients with tubal infertility who had experienced laparoscopic surgery were enrolled and were randomly divided into two groups (52 cases in each group) from August 2018 to July 2019. All patients had received propofol combined with remifentanil and cisatracurium besilate for general anesthesia. 30 minutes before the end of the operation, the patients in the control group were given fentanyl injected intravenously, and the patients in the observation group were given patazoxin injected intravenously. The Prince Henry Pain Score (PHPS), ramsay sedation score, sex hormone levels, and the rate of adverse reaction of the patients were compared between the two groups. Results: There were no significant different in the PHPS and the ramsay sedation score at postoperative T1, T2, T3, T4, and T5 of the patients between the two groups (P＞0.05). After operation, the levels of FSH, LH, and E2 of the patients in the two groups had increased significantly (P＜0.05), but which had no significant different before and after operation between the two groups (P＞0.05). The incidence of adverse reaction of the patients in the control group was 19.2％, which was significant higher than that (5.8％) of the patients in the observation group (P＜0.05). Conclusion: Pentazocine maintenance anesthesia for treating infertility patients after laparoscopic surgery under general anesthesia has definite analgesic effect, which has lower incidence of postoperative adverse reactions, and has the same influence on the sex hormone levels of patients when compared to those of fentanyl.
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