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| Value of color Doppler ultrasonography for evaluating fetal middle cerebral artery blood flow of twin to twin transfusion syndrome |
| Zigong Maternal and Child Health Care Hospital, Sichuan Province, 643000 |
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Abstract To analyze the value of color Doppler ultrasonography for evaluating fetal middle cerebral artery blood flow of twin to twin transfusion syndrome (TTTs). Methods: The data of 66 pregnant women diagnosed as TTTs between March 2013 and March 2018 were retrospectively. These women were included in research group, and another 66 pregnant women with normal twins were included in control group during the same period. The estimated fetal body weight of blood recipient fetus and blood donor fetus when admitted to hospital, the maximum vertical amniotic fluid depth, the fetal age when birth, the birth weight, the blood flow velocity of umbilical vein and umbilical artery, the middle cerebral artery peak systolic velocity (MCA-PSV), umbilical artery pulsation index (UA-PI), middle cerebral artery pulsation index (MCA-PI), and cerebroplacental ratio (CPR) of women in the research group were measured by ultrasonography. Results: In the research group, the estimated fetal body weight when admitted to hospital, maximum vertical amniotic fluid depth, birth weight, and the heart rate per minute, left chest area ratio, and left and right cardiac work index of the blood donor fetus were significant lower than those of the blood recipient fetus (all P<0.05). The levels of MCA-PSV, MCA-PI and CPR of fetal brain of women in the research group were significant lower than those of women in the control group. In the research group, the levels of MCA-PSV, MCA-PI and CPR of fetal brain of the blood recipient fetus were significant lower than those of the blood donor fetus. The UA-PI level of fetal brain of women in the research group was significant higher than those of women in the control group. In the research group, the UA-PI level of fetal brain of the blood recipient fetus was significant lower than that of the blood donor fetus (all P<0.05). Conclusion: Color Doppler ultrasonography can evaluated fetal middle cerebral artery blood flow of the blood recipient fetus of women with TTTs, and the change of fetal middle cerebral artery blood flow suggests that the fetal cerebral blood flow of women with TTTs has a paroxysmal transitional filling feature.
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