To analyze the diagnostic value of uterine artery color Doppler ultrasound combined with ultrasound elastography for endometriosis (EMS) of patients. Methods: The clinical data of 103 patients with EMS who were treated in hospital were collected in observation group, and 56 women without EMS confirmed by ultrasound examination were collected in control group from July 2018 to December 2023. All the patients in the two groups received uterine artery color Doppler ultrasound and ultrasound elastography, and the imaging characteristics of the EMS examined by uterine artery color Doppler ultrasound and ultrasound elastography of the patients were analyzed. The values of the uterine artery blood flow parameters, such as end-diastolic velocity (EDV), peak systolic velocity (PSV), pulsatility index (PI) and resistance index (RI), and the values of the ultrasound elastography parameters, such as shear wave velocity (SWV), mean elastic modulus (Emean), minimum elastic modulus (Emin) and maximum elastic modulus (Emax) of the patients were compared between the two groups, and the diagnostic values of the all above parameters for EMS of the patients were analyzed. Results: The values of EDV and PSV of the patients in the observation group were significantly lower than those of the patients in the control group, and the values of PI, RI, SWV, Emean, Emin and Emax of the patients in the observation group were significantly higher than those of the patients in the control group (all P<0.05). The EMS lesions were most (89.3%)  irregular in shape, and 86.4% EMS lesions of which distributed to the fascia or the full layer of the abdomen, 57.3% EMS lesions had small amount of blood flow signal in the lesion, 81.6% EMS lesions was hypoechoic, 76.7% EMS lesions was the uneven echo and 74.8% EMS lesions had the unclear lesion boundary. The values of uterine artery Doppler parameters and the ultrasound elastography parameters of the patients for predicting their EMS had good efficacy, and among them, the RI value had the highest predictive efficiency. When the cut-off value of the RI value of the patients for predicting their EMS was >0.82, the Youden index, the area under the curve, the sensitivity and the specificity were 0.734, 0.921, 92.2%, and 76.8%, respectively. Conclusion: The lesions of EMS of the patients are mostly irregular in shape, are mostly distributed to the fascia or the whole layer of the abdomen, are the small amount of blood flow signal in the lesion, are the hypoechoic and are the uneven echo and the unclear lesion boundary. Both the values of the uterine artery color Doppler ultrasound and the ultrasound elastography parameters of the patients can be used as the effective indicators for predicting their EMS.