|
|
|
| Application of thyroid function detection in pregnant women with hypothyroidism, and its effect on pregnancy outcomes |
| Panzhihua Integrated Traditional Chinese and Western Medicine Hospital, Sichuan Province,617000 |
|
|
|
|
Abstract Objective: To investigate the application of thyroid function detection in pregnant women with hypothyroidism, and to study its effect on pregnancy outcomes. Methods: A total of 436 pregnant women who were screened for gestational thyroid disease were enrolled. According to thyroid hormone levels, the women were divided into the observation group (218 pregnant women with high level of thyroid hormone) and the control group (218 pregnant women with normal level of thyroid hormone). The clinical indicators of thyroid hormone and pregnancy outcomes of women were compared between the two groups. Results: The positive rate of abnormal weight gain of women during pregnancy, immune diseases rate, rate of family history of diseases, cardiovascular symptoms, and rate of small fetus found by ultrasound of women in the observation group were 23.9%, 9.6%, 6.9%, 8.7%, and 33.5%, respectively, which were significant higher than those of women in the control group (P<0.05). The levels of FT3 and FT4 of women during the third trimester pregnancy in both groups were lowest, and those of women during the first trimester pregnancy were highest, and those of women during pregnancy in the observation group were significant lower than those of women in the control group (P<0.05). The incidence of gestational diabetes mellitus, pregnancy-induced hypertension, premature rupture of membranes, and postpartum hemorrhage of women in the observation group were 27.1%, 12.8%, 11.5%, and 10.6%, respectively, which were significant higher than those of women in the control group (P<0.05). The incidence of malformation, fetal distress, premature infants and low birth weight infants in the observation group were 5.5%, 11.5%, 22.0%, and 28.9%, respectively, which were significant higher than those of women in the control group (P<0.05). Conclusion: Subclinical hypothyroidism of women during pregnancy can lead to pregnancy complications and increase the adverse maternal and neonatal outcomes. Thyroid function screening of pregnant women should be strengthened for improving pregnancy outcomes.
|
|
|
|
|
|
|
|
|
