|
|
|
| The influence of dydrogesterone or progesterone for treating women with threatened abortion on the pregnancy outcomes |
| 1. The second Affiliated Hospital of Liaoning university of Chinese Traditional Medicine, Liaoning Province, 110034; 2. Fushun General Hospital of Mining Bureau |
|
|
|
|
Abstract To investigate the influence of different regimens of dydrogesterone or progesterone for treating women with threatened abortion on pregnancy outcomes. Methods: 82 women with threatened abortion were selected as study subjects from February 2017 to February 2018, and were randomly divided into control group and observation group (41 cases in each group) according to random numbers table. The women in control group were treated by dydrogesterone, and the women in observation group were treated by progesterone. The clinical curative effect of women was compared between the two groups. The changes of levels of serum progesterone (P) and β-human chorionic gonadotropin (β-hCG), pregnancy outcomes, and drug safety of women in both groups were observed before and after treatment. Results: The overall curative effect of women had no significant different between the two groups (P>0.05). There was no significant different in levels of P and β-hCG between the two groups before and after treatment (P>0.05), but the levels of P and β-hCG of women in both groups were significantly increased after treatment (P<0.05). The rate of continually pregnancy of women in observation group had no significant different that of women in control group (P>0.05). The total incidence of adverse reactions of women in observation group was significant lower than that of women in control group (P<0.05). Conclusion: Dydrogesterone and progesterone are similar efficacy for treating women with threatened abortion, which can regulate hormone and improve the pregnancy outcomes. However, progesterone has more advantages in terms of drug safety, so it is worthy of clinical application.
|
|
|
|
|
|
|
|
|
