To observe the hope level of women with repeated assisted reproduction, and to explore its related influencing factors. Methods: From May 2022 to June 2023, the infertile women who received repeated assisted reproductive technology in hospital were selected as the subjects. Herth hope index scale (HHI) was used to investigate the hope level of the women. The Chinese version of the event-related rumination inventory (C-ERRI) was used to assess the coping style of the rumination of the women. Simplified medical coping style questionnaire (SCSQ) was used to evaluate the coping style of the women. Perceived social support scale (PSSS) was used to evaluate the social support assess coping style of the women. The clinical data of the women were collected by general data questionnaire to analyze the possible influencing factors of the hope level of the women with repeated assisted reproduction. Pearson correlation coefficient model was used to analyze the correlation between the score of C-ERRI purposive rumination and invasive rumination, PSSS, SCSQ negative coping and positive coping of the women and their HHI score. Multiple linear regression model was used to analyze the influencing factors of the hope level of the women with repeated assisted reproduction. Results: A total of 235 questionnaires were distributed, and 219 were effectively recovered, with an effective recovery rate of 93.2%. The HHI score of the women with repeated assisted reproduction was 32.49±4.86 points, of which, 20(9.1%) cases  were at high level, 188(85.8%) cases were at middle level and 11(5.0%) cases were at low level. Pearson correlation analysis showed that SCSQ negative coping score of the women was negatively correlated with their HHI score, and the scores of C-ERRI purposive rumination, PSSS and SCSQ positive coping score of the women were positively correlated with their HHI score (all P<0.05). Multivariate linear regression analysis showed that the advanced age, the long duration of infertility, the long treatment cycle, the insufficient purposive rumination, the poor social support and the coping style of the women with repeated assisted reproductive technology were the main influencing factors of their hope level (all P<0.05). Conclusion: The hope level of the women with repeated assisted reproduction in this survey is at a medium level. The Age, duration of infertility, treatment cycle, purposive rumination, social support and coping style of the women with repeated assisted reproduction are all the influencing factors of their hope level, so the relevant countermeasures should be taken in clinic.