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Analysis of the characteristics and the risk factors of the nosocomial infection of neonates with body weight ≤1000g |
Women's and Children's Hospital Affiliated to School of Medicine, University of Electronic Science and Technology of China /Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan Province, 611731 |
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Abstract To explore the characteristics and the risk factors of the nosocomial infection of neonates with body weight≤1000g. Methods: 232 neonates with body weight ≤1000g who had delivered in the hospital were selected as the research subjects from January 2020 to December 2023. According to the infection status of the neonates, these neonates were divided into study group(63 neonates with nosocomial infection) and control group(169 without nosocomial infection). The characteristics of the nosocomial infection of these neonates were analyzed, and the high-risk factors of the nosocomial infection of these neonates were analyzed by multivariate Logistic regression analysis. Results: There were 63 neonates with the nosocomial infection in 232 neonates, and with the incidence was 27.2%. The main infection sites of the neonates were the lower respiratory infection(52.4%) and the ventilator-associated pneumonia(25.4%). A total of 48 pathogens of the nosocomial infection were detected, and the top three of which were Enterobacter cloacae(14.6%), Klebsiella pneumoniae(14.6%) and Escherichia coli(12.5%). Multivariate logistic regression analysis showed that the surgery, the prolonged hospitalization, the mechanical ventilation and the placement of central venous catheter of the neonates were the independent risk factors of their nosocomial infection. Conclusion: The lower respiratory tract infection is the more common nosocomial infection of the neonates with body weight ≤1000g. It is necessary to pay attention to the neonates with low birth weight who have undergone surgery, long hospitalization time, long-term ventilator-assisted breathing of long-term placement of central venous catheter in clinic.
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