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| Value of the body mass index combined with the plasma fibrinogen level of pregnant women with preeclampsia at delivery for assessing their postpartum deep vein thromboembolism |
| Cangzhou Maternal and Child Health Care Hospital, Cangzhou, Hebei Province, 061000 |
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Abstract To investigate the value of body mass index (BMI) combined with the plasma fibrinogen (FIB) level of pregnant women with preeclampsia (PE) at delivery for assessing their postpartum deep vein thromboembolism (DVT). Methods: The clinical data of 70 pregnant women with PE from March 2021 to September 2022 were collected retrospectively. These women were divided into group A (16 women with DVT) and group B (54 without DVT) according to the presence or absence of postpartum DVT of the women. The clinical characteristics of the women were compared between the two groups. The risk factors of the postpartum DVT and the value of the BMI value combined with the plasma FIB level at delivery for predicting the postpartum DVT of the pregnant women with PE were analyzed. Results: The proportions of the pregnancy thrombosis history, the bed rest time during puerperium ≥72h and the BMI ≥30kg/m2 of the women in group A were significantly higher than those of the women in group B, and the FIB level (5.3±0.7 g/L) of the women in group A was significantly higher than that (4.6±0.6 g/L) of the women in group B (all P<0.05). The history of thrombosis, the bed rest time during puerperium >72h, the BMI≥30kg/m2, and the increased plasma FIB level of the women with PE were the independent risk factors of their postpartum DVT occurrence (P<0.05). The area under the ROC curve of the BMI≥30kg/m2, the plasma FIB level, and the combination of the BMI ≥30kg/m2 and the plasma FIB level of the women with PE at delivery for predicting postpartum DVT were 0.654, 0.744 and 0.836, respectively, and which of the combination of the BMI≥30kg/m2 and the plasma FIB level of the women at delivery was significantly higher than that of the BMI≥30kg/m2 or the plasma FIB level alone. Conclusion: The BMI≥30kg/m2 at delivery and the high plasma FIB level of the pregnant women with PE are the risk factors of their postpartum DVT occurrence, therefore, the combination of the BMI≥30kg/m2 and the plasma FIB level of the women at delivery has certain predictive value for their postpartum DVT occurrence.
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