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| Impacts of labetolol and nifedipine combined with positive psychological intervention for treating pregnant women with hypertensive disorder complicating pregnancy on their blood pressure, negative emotions, and sleep quality |
| Yingshang County People's Hospital, Yingshang, Anhui Province, 236200 |
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Abstract To explore the impacts of labetolol and nifedipine combined with positive psychological intervention for treating pregnant women with hypertensive disorder complicating pregnancy (HDP) on their blood pressure, negative emotions, and sleep quality. Methods: A total of 100 pregnant women with HDP were randomly divided into two groups (50 cases in each group) from January 2022 to December 2023. The women in the two groups were given nifedipine combined with positive psychological intervention, and the women in the observation group were given labetolol additionally. The blood pressure value, the negative emotions situation, the sleep quality, the adverse pregnancy outcomes and the incidence of adverse reactions of the women were compared between the two groups. Results: After 4 weeks of treatment, the systolic blood pressure and diastolic blood pressure values of the women in the two groups had decreased significantly, and which (117.8±4.6 mmHg and 76.2±2.1mmHg) of the women in the observation group were significantly lower than those (130.3±5.4 mmHg and 83.0±3.2mmHg) of the women in the control group. The scores of the self-rating anxiety scale and self-rating depression scale of the women in the two groups had decreased significantly, and which (38.22±2.96 points and 40.38±2.54 points) of the women in the observation group were significantly lower than those (46.38±4.41 points and 51.36±3.88 points) of the women in the control group. The Pittsburgh sleep quality index score of the women in the two groups had decreased significantly, and which (6.22±0.94 points) of the women in the observation group was significantly lower than that (8.86±1.25 points) of the women in the control group (P<0.05). There was no significant difference in the incidence of adverse reactions (10.0% vs. 14.0%) of the women between the two groups (P>0.05). Conclusion: Labetolol and nifedipine combined with positive psychological intervention for treating the pregnant women with HDP can decrease their blood pressure, and improve their negative emotions and sleep quality.
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