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| Levels of interleukin 6, procalcitonin and fibrinogen of patients with torsion of ovarian cyst and their diagnostic values |
| Luojiang District People's Hospital of Deyang City, Deyang, Sichuan Province, 618500 |
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Abstract To investigate the expressions of interleukin 6 (IL-6), procalcitonin (PCT) and fibrinogen of patients with torsion of ovarian cyst, and to study their diagnostic values. Methods: The clinical data of 106 patients with ovarian cyst torsion (in study group) and 82 patients without ovarian cyst torsion (in control group) admitted to hospital from January 2020 to December 2022 were collected. The patients in the study group were divided into group A (patients with ovarian cyst necrosis) and group B (patients without ovarian cyst necrosis) according to the postoperative pathological results of the patients. The expression levels of IL-6, PCT and fibrinogen of the patients were compared among these groups, and their diagnostic values for the ovarian cyst torsion was analyzed. Results: The levels of IL-6 (12.8±0.6 pg/ml), PCT (0.6±0.1 ng/ml) and fibrinogen (3.0±0.8 g/L) of the patients in the study group were significantly higher than those (8.2±0.3 pg/ml, 0.1±0.0 ng/ml and 1.2±0.4 g/L) of the patients in the control group, and which of the patients in group A were significantly higher than those of the patients in group B (all P<0.05). Receiver operating characteristic curve analysis showed that the area under the curve of the IL-6 level, the PCT level, the fibrinogen level or the combination levels of IL-6, PCT and fibrinogen of the patients with ovarian cyst for diagnosing their torsion of ovarian cyst was 0.811, 0.891, 0.635 or 0.953, respectively. The sensitivity, the specificity and the accuracy of the combination levels of iIL-6, PCT and fibrinogen of the patients with ovarian cyst for diagnosing the torsion of their ovarian cyst were 98.1%, 92.3 and 89.8%, respectively. Conclusion: The combined levels of IL-6, PCT and fibrinogen of the patients with ovarian cyst for diagnosing their torsion of ovarian cyst has higher value, which can be used to guide the clinical practice.
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