To explore the application effect of the bean bag hot compress combined with the electroacupuncture used for analgesia of singleton women during full-term labor. Methods: A retrospective analysis was performed on the clinical data of the singleton women who had been given the analgesia during full-term labor from March 2020 to March 2023. According to whether the bean bag hot compress combined with electroacupuncture for the analgesia during delivery or not, these women were divided into observation group (216 cases with the bean bag hot compress combined with electroacupuncture for analgesia) and control group (190 cases with the simple electroacupuncture for analgesia). The hemodynamic status evaluated by heart rate (HR), mean arterial pressure (MAP) and blood oxygen saturation (SPO2), the levels of the analgesic indicators, such as serum catecholamine (CA), serum dynorphin (DYN) and cortisol (COR), the level changes of the stress degree indicators, such as adrenocorticotropic hormone (ACTH), norepinephrine (NE) and epinephrine (E), of the women before labor (T0) and in the first stage of labor (T1), in the second stage of labor (T2) and in the third stage of labor (T3) were compared between the two groups. Results: At T1, T2 and T3, the serum levels of DYN, MAP, and SPO2 of the women in the observation group were significantly higher than those of the women in the control group, while the HR value and the levels of COR and DA, and the stress indicators levels of the women in the observation group were significantly lower than those of the women in control group (all P<0.05). Conclusion: The bean bag hot compress combined with the electroacupuncture used for analgesia of singleton women during full-term labor can effectively relieve their body’ s stress response  and labor pain indicators, and which plays a positive role in maintaining their hemodynamic stability.