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| Effect of mifepristone combined with misoprostol for abortion of women with different gestational weeks |
| Zhoushan Women and Children Hospital, Zhoushan, Zhejiang Province, 316000 |
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Abstract To explore the effect of mifepristone combined with misoprostol for abortion of women with different gestational weeks. Methods: A total of 100 women who wanted medical abortion in hospital were selected and were divided into group A (46 women with 5 to 7 gestational weeks) and group B (54 women with gestational 8 to 12 weeks) according to the gestational weeks of these women from October 2022 to October 2023. All the women in the two groups were given mifepristone combined with misoprostol for medical abortion. The success rate of abortion, the natural discharge time of the pregnancy sac, the amount of vaginal bleeding, the time of vaginal bleeding, the adverse reactions rate and the changes of the sex hormone levels before and after treatment of the women in the two groups were analyzed. Results: The success rate of the abortion (97.8%) of the women in group A was significantly higher than that (83.3%) of the women in group B, and the amount of vaginal bleeding (71.1±8.1ml) and the vaginal bleeding time (8.0±0.9d) of the women in group A were significantly lower than those (169.1±10.8ml and 14.3±1.0d) of the women in group B. 1 week after abortion, the level of progesterone of the women in the two groups had increased significantly, the levels of estradiol and follicle stimulating hormone of the women in the two groups had decreased significantly, and the improvement effect of which of the women in group A was significantly better than that of the women in group B. The incidence of the adverse reactions (4.4%) of the women in group A was significantly lower than that (18.5%) of the women in group B (all P<0.05). Conclusion: Mifepristone combined with misoprostol for abortion of the pregnant women with less gestational weeks has better effect, which can improve the success rate of abortion, reduce the amount of vaginal bleeding, bleeding time and adverse reactions, and improve the level of the sex hormones of the women.
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