|
|
|
| Association between the fine particulate matter (PM2.5) exposure and its components for pregnant women and their risk of small for gestational age in Henan province |
| 1.School of Public Health, Zhengzhou University, Henan Province, 450001; 2.School of Public Health, Fudan University; 3.The Second Affiliated Hospital of Zhengzhou University; 4.Henan Institute of Reproduction Health Science and Technology, NHC Key Laboratory of Birth Defects Prevention; 5.The National Institutes of Family Planning |
|
|
|
|
Abstract To investigate the association between the fine particulate matter (PM2.5) exposure and its components for pregnant women and their risk of small for gestational age (SGA)in Henan province. Methods: A analysis was conducted on the maternal and infant data from the database of the women in Henan Province who had participated in National Free Preconception Health Examination Program (NFPHEP) in 2013. Logistic regression models were used to analyze the effects of the PM2.5 exposure of the pregnant women during different trimesters of pregnancy and the PM2.5 components during the entire trimester on their SGA. Results: After adjusting for the general demographic data, lifestyle, health behavior, pregnancy conditions and environmental temperature variables, compared to the exposure to the first quartile of PM2.5 concentration, the risk of delivering SGA of the women with the exposure to the fourth quartile of PM2.5 concentration during the first, the second and the third of pregnancy, and throughout the entire pregnancy had increased by 58.2% (OR=1.582, 95% CI 1.44-1.738), 35.4% (OR=1.354, 95% CI 1.235-1.483), 30.1% (OR=1.301, 95% CI 1.189-1.423), and 45.9% (OR=1.459, 95% CI 1.3631.561), respectively. Compared to the exposure to the first quartile of PM2.5 concentration, the risk of the delivering SGA of the women with the exposure to the fourth quartile of concentration of black carbon, organic matter, ammonium, nitrate and sulfate had increased (P<0.05). Conclusion: Avoiding PM2.5 exposure of the pregnant women during each trimester of pregnancy can reduce the risk of their SGA occurrence.
|
|
|
|
|
|
|
|
|
