Abstract To analyze and compare the effects of laparoscopic salpingotomy and salpingectomy for treating patients with tubal ectopic pregnancy on their fertility function and long-term prognosis. Methods: A total of 100 patients with tubal ectopic pregnancy were selected and were divided into two groups(50 cases in each group) according to the chronological order of admission from January 2019 to August 2022. The patients in group A were given salpingotomy and the patients in group B were given salpingectomy. The indicators related to surgery, the occurrence of postoperative complications, the tubal patency situation, the ovarian reserve function indicators, and intrauterine pregnancy rate within 3 years after surgery of the patients in the two groups were analyzed. Results: There were no significant differences in the recovery time of blood chorionic gonadotropin level and the length of hospital stay of the patients between the two groups(all P>0.05). The operation time(30.64±3.71 min) and the intraoperative blood loss(59.77±7.50 ml) of the patients in group B were significantly higher than those(21.38±3.04 min and 43.98±6.01 ml) of the patients in group A(all P<0.05). There was no significant difference in the incidence of postoperative complications(32.0% vs. 30.8%) of the patients between the two groups(P>0.05). The patency rate at least one fallopian tube(96.0%) of the patients in group A was significantly higher than that(80.0%) of the patients in group B. In 6 months after surgery, the levels of serum FSH(6.71±2.35 mIU/ml) and FSH/ luteinizing hormone(LH 1.49±0.37) of the patients in group B were significantly lower than those(8.41±3.79 mIU/ml and 2.19±0.44) of the patients in group B. The levels of estradiol(78.39±14.90 pg/ml) and anti-Mullerian hormone(4.36±1.96μg/L) of the patients in group B were significantly higher than those(50.74±19.02 pg/ml and 3.61±1.75μg/L) of the patients in group B. The intrauterine pregnancy rate(80.0%) and the ectopic pregnancy rate(18.0%) of the patients in group B within 3 years after surgery were significantly higher than those(54.0% and 6.0%) of the patients in group B(all P<0.05). Conclusion: Compared with those of laparoscopic salpingectomy, the laparoscopic tubal salpingotomy for treating the patients with tubal ectopic pregnancy has less influence on their fertility function.
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