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| Effect of Xueniaoan capsule combined with levofloxacin for treating female patients with urinary tract infection and its influence on the inflammatory factors |
| 1. School of Clinical Medicine, Guizhou Medical University, Guiyang, Guizhou Province, 550004；2. Guizhou Province People's Hospital |
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Abstract To explore the effect of Xueniaoan capsule combined with levofloxacin for treating female patients with urinary tract infection(UTI), and to study its influence on the inflammatory level and the adverse reactions of the patients. Methods: A total of 160 female patients with UTI were selected and divided into observation group(n=80) and control group(n=80) according to the random number table method from June 2020 to February 2023. The patients in the control group were treated with levofloxacin, and the patients in the observation group were treated with Xueniaoan capsule combined with levofloxacin. The clinical efficacy, the urine index, the inflammation level, the vaginal PH value and the incidence of adverse reactions of the patients in the two groups were observed. Results: The clinical efficacy(92.5%) of the patients in the observation group was significantly higher than that(81.3%) of the patients in the control group. The urine white blood cells counts and the urine bacteria level of the patients in the two groups after treatment had decreased significantly, and which(3.44±1.02 pieces /HP and 665.45±122.53 /μl) of the patients in the observation group were significantly lower than those(7.67±2.11 /HP and 934.61±158.35 /μl) of the patients in the control group. The levels of C reaction protein, high mobility group protein B1 and calcitonin of the patients in two groups after treatment had decreased significantly, and which(12.32±5.45 mg/L, 60.04± 12.44 ng/ml and 0.54±0.12 ng/ml) of the patients in the observation group were significantly lower than those(20.32±8.78 mm mg/L, 82.63±15.51 ng/ml and 2.13±0.43 ng/ml) of the patients in the control group. The vaginal PH value of the patients after treatment had decreased significantly, and which(4.54±0.77) of the patients in the observation group was significantly lower than that(5.23±0.85) of the patients in the control group. The total incidence of adverse reactions(7.5%) of the patients in the observation group was significantly lower than that(18.8%) of the patients in the control group(all P<0.05). Conclusion: Xueniaoan capsule combined with levofloxacin for treating the patients with UTI can improve their clinical efficacy, effectively alleviate their inflammation, and reduce the vaginal PH value and the incidence of adverse reactions.
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