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| Clinical application of blood routine examination combined with glycosylated hemoglobin of pregnant women for early diagnosing their gestational diabetes mellitus complicated with iron deficiency anemia |
| Zongyang County People's Hospital, Anhui Province, 246700 |
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Abstract To explore the value of blood routine examination combined with glycosylated hemoglobin (HbA1c) of pregnant women for early diagnosing their gestational diabetes mellitus (GDM) complicated with iron deficiency anemia. Method: 96 pregnant women with GDM complicated with iron deficiency anemia were selected in study group, and 96 pregnant women with GDM only were selected in control group from December 2019 to December 222. Logistic regression analysis was used to analyze the related factors affecting the occurrence of iron deficiency anemia of the women with GDM. The diagnostic value of blood routine combined with HbA1c for the women with GDM complicated with iron deficiency anemia was analyzed by receiver operating characteristic (ROC) curve. Results: The values of red blood cell count (RBC), mean volume of red blood cell (MCV), hemoglobin (Hb), and mean erythrocyte hemoglobin (MCH) of the women in the study group were significantly lower than those of the women in the control group, and the values of red blood cell distribution width (RDW) and HbA1c of the women in the study group were significantly higher (P＜0.05). There were no significant differences in the age, the body mass index (BMI), the number of pregnancies, the previous delivery history, and the abnormal times of antenatal examination of the women between the two groups (P＞0.05). The proportions of the bad dietary habit and during the third trimester of pregnancy of the women in the study group were significantly higher than those of the women in the control group (P＜0.05). The bad dietary habit, during the third trimester of pregnancy, and the abnormal increases of RDW and HbA1c of the women with GDM were all the risk factors of their iron deficiency anemia, and the normal values of RBC, MCV, Hb, and MCH of the women with GDM were the protective factors of their iron deficiency anemia (all P＜0.05). The area under the curve (AUC) of the blood routine indexes values combined with the HbA1c level of the women with GDM for diagnosing their iron deficiency anemia was 0.888, with the highest specificity (88.5%), and which was significantly better than that of the blood routine indexes values or the HbA1c level alone (all P＜0.001). Conclusion: The blood routine indexes values combined with the HbA1c level of the women with GDM for diagnosing their iron deficiency anemia has value.
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