Abstract To observe the efficacy of Buzhong yiqi decoction combined with magnetic stimulation for treating patients with mild uterine prolapse (UP), and to study the changes of the traditional Chinese medicine (TCM) syndrome score, the pelvic organ prolapses (POP-Q) score, and the pelvic floor electromyography (EMG) value. Methods: 114 patients with mild UP were divided into two groups (57 cases in each group) by the random number table method from June 2021 to October 2022. The patients in the study group were treated with Buzhong yiqi decoction combined with magnetic stimulation, and patients in the control group were treated with magnetic stimulation alone. The efficacy, the TCM syndrome score before and after treatment, the POP-Q score, the pelvic floor EMG value, and the matrix metalloproteinase (MMPs) related indexes of the patients were compared between the two groups. Results: After treatment, the total effective rate (94.7%) of the patients in the study group was significantly higher than that (79.0%) of the patients in the control group. The total TCM syndrome score (2.30±0.56 points) of the patients in the study group was significantly lower than that (4.05±1.27 points) of the patients in the control group. The serum MMP-1 and MMP-2 levels of the patients in both groups after treatment had decreased significantly. The maximum EMG value and TIMP-2 level of type I and II muscle fibers of the patients in both groups after treatment had increased significantly, and which of the patients in the study group were significantly better than those of the patients in the control group. The POP-Q score of the patients in the study group after treatment was significantly better than that of the patients in the control group (all P<0.05). Conclusion: Buzhong yiqi decoction combined with magnetic stimulation for treating the patients with mild UP can increase the efficacy of treatment, and which can improve the clinical symptoms and POP-Q score, and can improve the pelvic floor EMG value recovery, and which may be related to the regulation of serum MMP-1, MMP-2, and TIMP-2 levels of the patients.
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