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| Effects of dezocine used in general anesthesia during laparoscopic surgery of patients on their postoperative extubation reaction and chills |
| Jiangsu Province Hospital of Chinese Medicine, Nanjing, Jiangsu Province, 210029 |
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Abstract To analyze the effects of dezocine used in general anesthesia during laparoscopic surgery of patients on their postoperative extubation reaction and chills. Methods: A total of 93 patients who wanted laparoscopic surgery under general anesthesia were selected as the study subjects and were randomly divided into study group (n=46)and control group (n=47)from January 2021 to December 2021. The patients in the study group were given intravenous injection of dezocine 0.1mg/kg within half an hour before the end of the surgery, while the patients in the control group were given intravenous injection of the same amount of normal saline. The changes of the hemodynamic and Ramsay sedation score of the patients in the two groups were observed before administration (T0), at 10min after administration (T1), immediately after extubation (T2), and at 5min after extubation (T3). The occurrence of extubation reactions, such as coughing and agitation, the operation time, the awakening time, the chills situation evaluated by Wrench, and the postoperative adverse reactions of the patients in the two groups were observed. Results: The scores of hemodynamics and Ramsay sedation of the patients in the study group at T1, T2, and T3 were significantly lower than those of the patients in the control group. The incidence of extubation reaction (4.4%)of the patients in the study group was significantly lower than that (19.2%)of the patients in the control group (P＜0.05). There were no significant differences in the operation time and the awakening time of the patients between the two groups (P＞0.05). The incidence of postoperative chills (40.4%)of the patients in the control group was significantly higher than that (13.0%)of the patients in the study group (P＜0.05). The incidence of adverse reactions within 24 hours after surgery (25.5%)of the patients in the study group was not different from that (17.4%)of the patients in the control group (P＞0.05). Conclusion: The intraoperative application of dezocine in general anesthesia during laparoscopic surgery of the patients can significantly reduce the incidences of their extubation reaction and postoperative chills, and which can effectively stabilize the changes of intraoperative hemodynamic and the depth of sedation of the patients.
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