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| Comparison of the pregnancy outcomes of the induction of labor of pregnant women with suspected macrosomia during 39 gestational weeks and 41 gestational weeks |
1.Beijing Amcare Wanliu Women’s & Childrens’Hospital, Beijing, 100089; 2.Beijing Shangdi Hospital;
3. Beijing Amcare Beisanhuan Women’s & Childrens’Hospital |
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Abstract To explore the best induction timing of pregnant women with suspected macrosomia by comparing the pregnancy outcomes of the women who undergone selective induction of labor during 39 gestational weeks and during 41 gestational weeks. Methods: A controlled prospective clinical trial was conducted to select 726 singleton pregnant women with suspected macrosomia and vertex presentation during 39 gestational weeks in this study from July 1st, 2018 to June 30th, 2021. These women were divided into two groups according to their personal wishes, which included 298 women with selective labor induction during 39 gestational weeks in observation group, and the other 428 women who still hadn’t delivered till 41 gestational weeks and had selective labor induction during 41 gestational weeks in control group. The outcomes of the mothers and infants were observed and compared between the two groups. Results: The rate of cesarean section (18.8%) of the women in the study group was significantly lower than that (45.6%) of the women in the control group. The body weight of newborns (4030±485g), the rate of macrosomia (75.5%)，the incidence of neonatal 5 min Apgar score <7 point (3.7%), and the neonatal umbilical artery blood PH <7.20 (3.0%) of the women in the observation group were significantly lower than those (4180±465g, 92.5%, 5.1%, and 14.4%) of the women in the control group (P<0.05). Conclusion: For the pregnant women with suspected macrosomia, the selective induction of labor during 39 gestational weeks can increase the rate of their successful vaginal delivery without increasing the incidence of the adverse maternal outcomes，and can reduce the adverse infants outcomes.
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