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| Correlation between the ureaplasma urealyticum infection of pregnant women and their neonatal infection and adverse prognosis |
| Jiangyou People's Hospital, Jiangyou, Sichuan Province, 621700 |
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Abstract To explore the influence of ureaplasma urealyticum (Uu) infection of pregnant women during the first and the second trimester of pregnancy on their neonatal infection and prognosis. Methods: 59 pregnant women who had been diagnosed with Uu infection from October 2020 to December 2021 were collected in study group retrospectively, and 76 healthy pregnant women were enrolled in control group during the same period. The baseline data, the situation of neonatal Uu infection, and the adverse maternal-infant outcomes of the women were compared between the two groups. The relationship between the delivery mode of the women in the study group and their neonatal Uu infection was analyzed, and the influencing factors of the poor neonatal outcomes was also analyzed. Results: There were no significant differences in the age, the body mass index, the gravidity, the parity number, gestational weeks, and educational level of the women between the two groups (P＞0.05), there was significant difference in the delivery mode of the women between the two groups (P＜0.05). The rate of neonatal Uu infection (40.7%) in the study group was significantly higher than that (2.6%) of the women in the control group (P＜0.05). In the study group, there was no significant difference in the rate of neonatal Uu infection (57.1% vs. 53.3% vs.32.4%) among the women with vaginal assisted delivery, the women with natural delivery, and the women with caesarean section (P＞0.05). The incidences of premature rupture of membranes (22.0%), the premature delivery (13.6%), the fetal distress (13.6%), the neonatal asphyxia (18.6%), and the low birth weight (17.0%) in the study group were significantly higher than those (7.9%, 5.3%, 4.0, 6.6%, and 4.0%) in the control group (P＜0.05). Logistics regression analysis showed that the positive Uu of the pregnant women was associated with their poor neonatal outcomes (P＜0.05). Conclusion: The Uu infection of the pregnant women has a high maternal-infant vertical infection rate, and which can increase the risk of adverse maternal and infant outcomes, so it needs to be paid attention to in clinical practice.
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