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| Effect of misoprostol combined with lidocaine for intrauterine device removal of menopausal women |
| 1. Qiongshan District Maternal and Child Health Care Hospital, Haikou, Hainan Province, 571100； 2. Haikou Maternal and Child Health Care Hospital；3. Hainan Women and Children Medical Center |
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Abstract To explore the influence of misoprostol combined with lidocaine used in the intrauterine device (IUD) removal of menopausal women on their operation time, the pain degree, and the success rate of IUD removal. Methods: A total of 92 menopausal women who wanted IUD removal in the hospital were enrolled and were randomly divided into group A (46 women with misoprostol combined with lidocaine used during IUD removal) and group B (46 women with misoprostol used alone during IUD removal) between January 2020 and January 2022. The intraoperative conditions (operation time, intraoperative blood loss, and intraoperative pain), the degree of cervical softening, the success rate of IUD removal, and the medication safety of the women were compared between the two groups. Results: The operative time (4.93±0.87 min), the intraoperative blood loss (3.62±0.65 ml), and the intraoperative pain visual analog score (1.99±0.43 points) of the women in group A were all significantly lower than those (7.54±1.02 min, 7.01±1.10 ml, and 5.17±0.90 points) of the women in group B. The rate of successful cervical softening (93.5%) and the success rate of IUD removal (97.8%) of the women in group A were significantly higher than those (78.3% and 87.0%) of the women in group B (all P＜0.05). There was no significant difference in the incidence of adverse drug reaction (10.9% vs. 6.5%) of the women between the two groups (P＞0.05). Conclusion: The application of misoprostol combined with lidocaine for IUD removal of the menopausal women can improve their cervical softening, reduce their intraoperative blood loss, shorten their operation time, increase their success rate of IUD removal, and can greatly relieve their intraoperative pain, with better safety.
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