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Abstract To explore the effect and difficulty of transvaginal endoscopic surgery for treating patients with myoma of uterus. Methods: A total of 210 patients with myoma of uterus from October 2018 to October 2021 were selected and were divided into observation group (women treated by transvaginal endoscopic surgery) and control group (women treated by single hole transumbilical laparoscopy). The perioperative indexes, the postoperative biochemical indexes, the visual analog score (VAS) in postoperative 24h, and the incidence of complications of the patients were compared between the two groups. Results: There were no significant differences in the operation time and the intraoperative blood loss of the patients between the two groups (P>0.05). Te exhaust time (25.4±3.6 h) and the hospital stay (3.2±0.7 d) of the patients in the observation group were significantly shorter than those (31.7±4.6 h and 4.3±0.9 d) of the patients in the control group (P＜0.05). There was no significant difference in VAS score of the patients at the 6th hour after operation between the two groups. The VAS scores of the patients at the 12th and at the 24th hour after operation (4.24±0.98 points and 3.13±0.72 points) in the observation group were significantly lower than those (4.67±1.09 points and 4.13±0.69 point) of the patients in the control group (all P＜0.05). There was no significant difference in the incidence of surgical complications (1.0% vs. 3.8%) of the patients between the two groups (P>0.05). The levels of MDA (67.87±10.35 umol/L) and SOD (7.82±2.42 U/ml) of the patients in the observation group were significantly were better than those (75.24±7.38 umol/L and 4.77±1.03 U/ml) of the patients in the control group (all P＜0.05). Conclusion: Transvaginal endoscopic surgery for treating the patients with myoma of uterus is effective, which has better postoperative recovery and less complication.
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