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Abstract To explore the effect labor analgesia of spinal-epidural anesthesia of sufentanil combined with ropivacaine for women, and to study its influence on labor process and delivery modes of the women. Methods: Between March 2018 and March 2020, 102 primiparas were recruited and were divided into observation group (54 cases) and control group (48 cases) according to different labor analgesia. The primiparas in the control group received doula for analgesia in routine labor, while the primiparas in the observation group received spinal-epidural anesthesia combined with sufentanil and ropivacaine based on the treatments in the control group. The labor process, delivery modes, the neonatal Apgar scores, and the analgesic effects of the primiparas were compared between the two groups. Results: There were no significant differences in the time of the first, the second, and the third stages of labor, and the incidences of the fetal distress and the forceps delivery of the primiparas between the two groups (all P>0.05). The rate of cesarean section (9.3%) of the primiparas in the observation group was significantly lower than that (25.0%) of the primiparas in the control group (P＜0.05). There was no significant difference in VSA scores of the primiparas before analgesia between the two groups (P>0.05). The VSA scores of the primiparas in 30min, 60min, and 90min after analgesia in the observation group were 0.18±0.43 points, 0.58±1.43 points, and 2.14±2.52 points, respectively, which were significantly lower than those (7.84±2.56 points, 7.56±3.25 points, and 8.16±1.68 points, respectively) of the primiparas in the control group (all P＜0.05). The neonatal Apgar score in 1min and 5min in the observation group were 8.83±0.56 points and 9.34±0.38 points, which had no significantly different from those (8.72±0.38 points and 9.46±0.31 points) in the control group (P>0.05). Conclusion: Spinal-epidural anesthesia combined with sufentanil and ropivacaine for labor analgesia is conducive to reducing labor pain and cesarean section rate of the parturients without influence on the maternal and neonatal safety as well as the labor process, which is worthy of clinical application.
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