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| The influence of blastocyst formation time of women observed by time-lapse imaging system on their clinical outcomes |
| Taihe Hospital of Shiyan, Hubei Province, 442000 |
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Abstract To investigate the influence of the blastocyst formation time of women observed by time-lapse imaging system (TLIS) on their outcomes after blastocyst transplantation. Methods: From April 2019 to October 2021, 313 blastocysts of infertile women who received assisted reproductive therapy and blastocyst culture were selected as the research subjects. The formation time of the best quality blastocysts of these women was observed and recorded by TLIS. According to the time of blastocyst formation, these women were divided 177 women with less than 120 hours in group A , 88 women with 120-144 hours in group B, and 48 women with >144 hours in group C. The clinical outcomes of the women after cryopreservation embryo transfer were compared among the three groups. Results: The implantation rate, the clinical pregnancy rate, and the early abortion rate of the women in group A were 59.32%, 58.45% and 4.81%, respectively, and which of the women in group B were 55.68%, 55.68%, 6.12%, respectively, and which of the women in group C were 35.42%, 35.42%, 5.88%, respectively. The implantation rate, the clinical pregnancy rate, and the early abortion rate of the women in group A had no significant different from those of the women in group B (P>0.05), but which of the women in group A and group B were all significantly higher than those of the women in group C (P<0.05). There was no statistical significant difference in the abortion rate of the women among the three groups (P>0.05). Conclusion: The embryo dynamic development time by TLIS used to select the high-quality blastocysts in the rapid development of the embryo, which can significantly improve the outcomes of the women after embryo transfer.
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