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Significance of ultrasonic soft indexes for diagnosing abnormal fetal cardiac structure during11-14 gestational weeks |
Guang'an People's Hospital, Guang'an, Sichuan Province, 638400 |
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Abstract To study the clinical diagnostic significance of ultrasonic soft indexes for abnormal fetal cardiac structure during 11-14 gestational weeks. Methods: A retrospective analysis was performed on the clinical data of 107 pregnant women with singleton pregnancies who had received ultrasonic examination during 11-14 gestational weeks from May 2017 to September 2020. The ultrasonic soft indexes of these women were collected and were followed up to determine of their pregnancy. Base on the final pregnancy outcomes as the golden standard, the coincidence of soft indexes of ultrasonic examination and clinical diagnosis for fetal heart malformation was analyzed. Results: The sensitivity, the specificity, and the accuracy, the negative predictive value, the positive predictive value, and Kappa value of ultrasonic diagnosis of fetal cardiac malformation were 83.3%, 97.8%, 95.3%, 96.7%, 88.2%, and 0.829, respectively, which had better coincidence with the results of gold standard (P<0.05). The rate of abnormal soft indexes of ultrasonic examination of the fetus with heart malformation was significantly higher than that of the fetus with normal heart, and which of the pregnant women ≥30 years old was significantly higher than that of the pregnant women <30 years old (all P<0.05). TR reverse blood flow, NT thickening, abnormal DV blood flow spectrum, and maternal age ≥30 years old were all correlated with the fetal heart abnormalities and were all the independent risk factors of the fetal heart abnormalities (all P<0.05). Conclusion: The ultrasonic soft indexes for diagnosing fetal heart abnormalities during the first trimester of pregnancy has high efficiency, which is conducive to early accurate judge the fetal cardiac structure abnormalities.
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