|
|
|
| Clinical significance of serological indexes levels combined with the comprehensive assignment score of vaginal secretion index of pregnant women for predicting their premature rupture of fetal membrane complicated with chorioamnionitis |
| 1.Jinshui District General Hospital, Zhengzhou, Henan Province,450000; 2. The Second Affiliated Hospital of Zhengzhou University |
|
|
|
|
Abstract To analyze the values of serological indexes levels combined with the comprehensive assignment score of vaginal secretion index of pregnant women for predicting their preterm premature rupture of membranes (PPROM) complicated with histological chorioamnionitis (HCA). Methods: A total of 203 pregnant women with PPROM from January 2018 to December 2020 were collected retrospectively and were divided into group A (55 women with HCA) and group B (148 women without HCA) according to the histological diagnosis gold standard of HCA. Results: The values of serum white blood cell (WBC), neutrophil (NE), C-reactive protein (CRP), procalcitonin (PCT), as well as the incidences of positivegroup B streptococcus (GBS) in vaginal secretion, bacterial vaginal disease (BV), vulva vagina candida (VVC), trichomonas vaginitis (TV) of the women in group A were significantly higher than those of the women in group B (P<0.05), but there was no significant difference in the incidence of aerobic bacterial vaginitis (AV) in vaginal secretion of the women between the two groups (P>0.05). The values of serum indexes, such as WBC, NE, CRP, and PCT, and the indexes values of the vaginal secretion, such as GBS positive, BV, VVC and TV, of the women had predictive effects for HCA (P<0.05). After the scores assigned to the serum indexes and the vaginal secretion indexes, the score (5.8±2.1) of the women in group A were significantly higher (5.8±2.1) than that (3.7±1.8) of the women in group B (P<0.001). The comprehensive scores of the serum indexes and the vaginal secretion indexes of the women had efficacy for predicting their HCA occurrence (P<0.001). The area under the curve, the sensitivity, the specificity, and the optimal cut-off value of which were 0.841, 83.6%, 81.9%, and 6 points, respectively. Conclusion: The comprehensive assignment score of the serum indexes and the vaginal secretion indexes of the pregnant women with PPROM used for predicting their HCA has some clinical significance.
|
|
|
|
|
|
|
|
|
