|
|
|
| Maternal and fetal circulation situation evaluated by the uterine artery blood flow indexes of ultrasonography and their correlation with the pregnancy outcomes |
| South Branch of The Sixth People's Hospital of Shanghai, Shanghai, 201499 |
|
|
|
|
Abstract To explore the maternal and fetal circulation situation evaluated by the uterine artery blood flow indexes of ultrasonography, and to study their correlation with the pregnancy outcomes of the women. Methods: A total 69 pregnant women with preeclampsia were included as the research subjects from March 2018 to March 2021, which included 34 cases with mild preeclampsia in group A and 35 cases with severe preeclampsia in group B. In addition, 30 normal pregnant women were included in group C during the same time. The maternal and fetal blood flow parameters, the maternal-fetal circulation indicators by ultrasound, and the perinatal prognosis indicators in the three groups were examined. The blood flow parameter indexes included resistance index (RI) and pulsation index (PI) of umbilical artery and middle cerebral artery, maximum flow velocity (Vmax), internal diameter (Duv), and the ratio of peak systolic flow velocity to peak diastolic flow velocity (S/D) of venous and umbilical artery. The maternal and fetal circulation indicators by ultrasound included uterine artery PI, umbilical artery PI, middle cerebral artery PI, fetal venous catheter venous pulsation index (PIV), and cerebral placental blood flow ratio (CPR). And the perinatal prognosis indicators included gestational weeks at delivery, neonatal body weight, 5-minute Apgar score, umbilical artery PH, and placental weight. The blood flow parameters of fetus with different pregnancy outcomes were analyzed. The correlation between the fetal blood flow parameters and the adverse prognosis of the perinatal infants was analyzed by logistic regression. Results: The venous catheter diversion rate, and the values of umbilical artery PI, umbilical artery RI, and umbilical artery S/D in group B were significantly higher than those in group A and group C, and the values of middle cerebral artery PI, RI, and S/D in group B were significantly lower than those in group A and in group C (P<0.05). The values of uterine artery PI and umbilical artery PI in group B were significantly higher than those in group C and in group A, and the values of middle cerebral artery PI and CPR in group B were significantly lower than those in group C and in group A (P<0.05). The gestational weeks at delivery, the birth weight, the umbilical artery PH, Apgar score, and the placental weight of the perinatal infants in group B were significantly lower than those the perinatal infants in group A and in group C (P<0.05). Among 69 infants delivered by the pregnant women with preeclampsia, there were 21 cases (30.4%) with adverse outcomes. The venous catheter diversion rate, and the umbilical artery PI, umbilical artery RI, and umbilical artery S/D of the infants with adverse outcomes were significantly higher than those of the infants with normal pregnancy outcomes (P<0.05). Regression analysis showed that adverse perinatal prognosis was significantly correlated with the fetal venous catheter diversion rate, the values of PI, RI, and S/D of umbilical artery and middle cerebral artery (P<0.05). Conclusion: The ultrasound examinations of hemodynamic parameters of uterine artery of the pregnant women with preeclampsia, and the fetal umbilical artery, and the fetal middle cerebral artery and venous catheter can provide evidences for assessing fetal intrauterine conditions accurately in clinic, and which has certain correlation with the adverse pregnancy outcomes of the women with pregnancy induced hypertension.
|
|
|
|
|
|
|
|
|
