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| Analysis of the factors affecting endometriosis recurrence of patients with ovarian endometriosis after conservative surgery |
| Daxing District People's Hospital，Beijing, 102600 |
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Abstract To explore the factors affecting endometriosis recurrence of the patients with ovarian endometriosis after conservative surgery. Methods: The clinical data of 110 patients with ovarian endometriosis who had accepted the conservative surgery from November 2019 to November 2020 were selected. These patients were divided into two group A (35 patients with ovarian endometriosis recurrence) and group B (75 patients without ovarian endometriosis recurrence). The clinical data and pathological information, and other, of the patients were collected and analyzed. The factors affecting the recurrence of ovarian endometriosis of the patients after conservative surgery were explored. Results：The levels of tumor markers carbohydrate proteins, such as CA125 and CA199, and human epididymal protein 4 (HE4), the rates of preoperative adenocarcinoma, previous gynecological operation history, and tenderness nodules in cervix posterior fornix, and the proportion of r-AFS stage III or IV of the patients in group A were significantly higher than those of the patients in group B (all P<0.05). There was no significant difference in the ovarian bilateral lesion rate of the patients between the two groups (P>0.05). The rates of postoperative pregnancy and postoperative drug therapy of the patients in group A were significantly lower than those of the patients in group B (P<0.05). Logitic regression analysis showed that preoperative R-AFS stage, increased serum tumor marker level, preoperative complications, and previous gynecological surgery history were the independent risk factors of the postoperative ovarian endometriosis recurrence, while the postoperative pregnancy and postoperative drug therapy were the protective factors of the postoperative ovarian endometriosis recurrence. Conclusion：After conservative surgical treatment of the patients with ovarian endometriosis，multiple factors all induce the recurrence of endometriosis. Prevention and treatment should be done in accordance with the individual situation，so as to reduce the recurrence rate of ovarian endometriosis.
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