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| Analysis of the risk factors of the spontaneous premature delivery of pregnant women with gestational diabetes mellitus |
| Huiyang District Sanhe Hospital, Huizhou, Guangdong Province, 516211 |
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Abstract To investigate the risk factors of the spontaneous premature delivery (SPD) of pregnant women with gestational diabetes mellitus (GDM). Methods: 102 pregant women with GDM and SPD (in group A) and 102 pregant women with GDM and without SPD (in group B) were selected in this study from January 2019 to December 2020. The clinical data of the women were compared between the two groups. The risk factors of SPD were analyzed by logistic multivariate analysis. Receiver operating characteristic curve (ROC) was used to analyze the predictive value of the risk factors for SPD. Results: The values of the prepregnancy body mass index (BMI) and the advanced age when pregnancy, and the proportions of history of gestational infection, family diabetes, spontaneous abortion, and menstrual cycle disorder of the women in group A were significantly higher than those of the women in group B (P＜0.05). The high prepregnancy BMI value, the advanced age when pregnancy, the history of gestational infection, the history of family diabetes, and the history of spontaneous abortion were the independent risk factors of SPD (P＜0.05). ROC analysis showed that in all of the predictive indexes, the area under of curve (0.73) or the sensitivity (83%) of the pre-pregnancy BMI value for predicting SPD was the highest, and the specificity (75%) of the history of family diabetes for predicting SPD was the highest (P＜0.05). Conclusion: The risk factors related to GDM should be paid attention to, and which should be early intervented to reduce SPD in clinic.
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