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Abstract To study the epidemiological characteristics of gestational diabetes mellitus (GDM) of pregnant women and the correlation between GDM, and to study the correlation between GDM occurrence of the women and their pregnancy situation and adverse pregnancy outcomes. Methods: 960 pregnant women with GDM were selected as the research objects and were divided into group A (327 women during the first trimester of pregnancy), group B (319 women during the second trimester of pregnancy), and group C (314 women during the third trimester of pregnancy) according to the different pregnancy stages of the women diagnosed of GDM from January 2010 to December 2019. These women were further divided into group D (498 women with normal pregnancy outcomes) and group E (462 women with adverse pregnancy outcomes) according to the different pregnancy outcomes, and the epidemiological characteristics of the women were compared between group D and group E. Spearman correlation analysis was used to analyze the correlation between the pregnancy situation and the adverse pregnancy outcomes of the women and their epidemiology of GDM. The multivariate logistic analysis was used to analyze the adverse pregnancy outcomes of the women. Results: There were no significant differences in age, the pre-pregnancy body mass index (BMI) value, the average monthly income, the occupation, the education level, and the waist-hip ratio in the first antenatal examination among the women in different pregnancy stages and among the women with different pregnancy outcomes (P>0.05). There were significant differences in the weight gain during pregnancy, the rate of weight gain during pregnancy, and the values of the waist circumference, hipline and BMI in the first antenatal examination among the women in different pregnancy stages and among the women with different pregnancy outcomes (P<0.05). The weight gain during pregnancy, the rate of weight gain during pregnancy, and the values of BMI, waist circumference and, hipline in the first antenatal examination of the women were positively correlated their pregnancy situation and the adverse pregnancy outcomes, which were all the independent risk factors of their adverse pregnancy outcomes (P<0.05). Conclusion: The weight gain during pregnancy, the rate of weight gain during pregnancy, and the values of waist circumference, hipline, and BMI of the pregnant women in the first antenatal examination during the third trimester of pregnancy are all significantly higher than those during the first trimester of pregnancy, and which all the independent risk factors of their adverse pregnancy outcomes, so these pregnant women should be focused on their weight management during pregnancy. The screening, and the prevention and treatment of GDM of the pregnant women should be done to reduce their adverse pregnancy outcomes.
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