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| Efficacy of self-designed prescription combined with ethinylestradiol and cyproterone acetate tablets for treating infertile women with polycystic ovary syndrome |
| The Second People’s Hospital of Yibin，Sichuan Province, 644000 |
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Abstract To explore the influence of self-designed prescription combined with ethinylestradiol and cyproterone acetate tablets for treating infertile women with polycystic ovary syndrome (PCOS) on their sex hormone level and pregnancy outcomes. Methods: 80 women with PCOS were selected and were randomly divided into control group and observation group (40 cases in each group) from January 2019 to October 2019. The women in the control group were treated by ethinylestradiol and cyproterone acetate tablets, while the women in the observation group were treated by self-designed prescription combined with ethinylestradiol and cyproterone acetate tablets. The serum sex hormone levels, ovulation situation, and pregnancy outcomes, clinical efficacy, and adverse reactions rate of the women in the two groups were analyzed. Results: After treatment, the levels of luteinizing hormone (6.51±1.60 U/L), follicle stimulating hormone (2.11±0.92 U/L), testosterone (1.50±0.4 ng/mL), and estradiol (60.48±8.51 pmol/L) of the women in the observation group were significant lower than those of the women in the control group. The ovulation rate (87.5%) and pregnancy rate (62.5%) of the women in the observation group were significant higher than those (57.5% and 32.5%) of the women in the control group, and the total effective rate (85.0%) of the women in the observation group was significant higher than that (62.5%) of the women in the control group (all P＜0.05). There was no significant difference in the rate of adverse reaction (7.5% vs. 10.0%) of the women between the two groups (P＞0.05). Conclusion: The self-designed prescription combined with ethinylestradiol and cyproterone acetate tablets for treating infertile women with PCOS can effectively improve the levels of sex hormones, promote the ovulation, and improve the pregnancy rate.
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