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| Evaluation of left ventricular function changes of patients with severe preeclampsia by ultrasound velocity vector imaging combined with amino terminal brain natriuretic peptide precursor |
| 1.Jinhua People's Hospital, Jinhua, Zhejiang Province, 321015；2. The First People's Hospital of Nanyang, Affiliated to Henan University, Nanyang |
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Abstract To explore the evaluation of left ventricular function changes of patients with severe preeclampsia by ultrasound velocity vector imaging (VVI) combined with amino terminal brain natriuretic peptide precursor (NT proBNP). Methods: 57 pregnant women with severe preeclampsia (in study group) and 64 normal pregnant women (in control group) were selected in this study from January 2019 to March 2020. Echocardiography and VVI technique were used to detected the values of the left ventricular related parameters of the women in the two groups, which included left atrium inner diameter (LAD), ventricular septal thickness (IVSD), end diastolic left ventricular diameter (LVD), left ventricular ejection fraction (EF), early diastolic maximum cardiac blood flow velocity (E)/ late diastolic maximum cardiac blood flow velocity (A), E/ early diastolic tissue movement velocity (e ′), left ventricular systolic overall long axis strain (S), strain rate (SRs), and diastolic overall longaxis strain rate (SRd). The plasma NT proBNP level of the women in the two groups was tested, and the adverse pregnancy outcomes of the women in the two groups were recorded. Results: The systolic and diastolic blood pressure values, and the values of LAD, IVSD, LVD, and E/e ' of the women in the study group were significantly higher than those of the women in the control group (P＜0.05). While the values of EF and E/A of the women in the study group were significantly lower than those of the women in the control group. The measure values of VVI indictors, such as S (13.67±5.39) %, SRs (0.72±0.29/S), and SRd (0.76±0.24/S), of the women in the study group were significantly lower than those (23.36%±5.87%, 0.72±0.29/S, 1.47±0.53/s) of the women in the control group, and the NT proBNP (2.11±0.43 pg/ml) value of the women in the study group was significantly higher than that (1.57±0.32 pg/ml) of the women in the control group (P＜0.05). The measurement values of VVI of the women in the study group were negatively correlated with their blood NT proBNP level (P＜0.05). The incidences of fetal growth restriction, preterm delivery, and placental abruption of the women in the study group were significantly higher than those of the women in the control group (P＜0.05). Conclusion: The measurement value of VVI and blood NT proBNP level of the women with severe PE are abnormal, and there is correlation between the measurement value of VVI and the blood NT proBNP level.
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