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| Effects of sub-anesthetic dose of esmketamine auxiliary used during cesarean section on the postoperative analgesics consumption |
| 1. Northwest Women's and Children's Hospital, Xi 'an, Shaanxi Province, 710061；2. Baoji Central Hospital, Shaanxi Province |
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Abstract To investigate the effects of sub-anesthetic dose of esmketamine auxiliary used during cesarean section on the postoperative analgesics consumption. Methods: 78 pregnant women who wanted cesarean section were randomly selected and were divided into two groups by random number table from June 2021 to March 2022. The women in the observation group were given sub-anesthetic dose of esmketamine auxiliaryly during cesarean section additionally. The total consumption of analgesic naborphine at 24 hours and 48 hours after operation, the time of complete awakening, the time of the first postoperative eating, the onset time of analgesia and the recovery time of anesthesia, the anesthetic effect, and the adverse reactions of the women were compared between the two groups. Results: The nalbuphine consumption within 24 and 48 hours after operation(30.6±6.5mg and 54.8±11.4mg)of the women in the observation group were significantly lower than those(24.1±6.3mg and 41.5±12.9mg)of the women in the control group(all P＜0.05). The onset time and recovery time of anesthesia of the women had no significant differences between the two groups(P＞0.05). The total effective rate of anesthesia(100.0%)of the women in the observation group was significantly higher than that(87.2%)of the women in the control group. The time of patient-controlled intravenous analgesia(PCIA)pump used and the postoperative analgesia satisfaction of the women in the observation group were significantly better than those of the women in the control group. The first time to eat after operation of the women in the observation group was significantly shorter than that of the women in the control group(P＜0.05). The total incidence of adverse reactions(7.7%)of the women within 24 hours after operation had no significantly different from that(10.3%)of the women in the control group(P＞0.05). Conclusion: The sub-anesthetic dose of esmketamine auxiliary used during cesarean section can effectively reduce the consumption of postoperative analgesics, improve the effect of analgesia and anesthesia during cesarean section, and enhance the comfort and satisfaction of the pregnant women during perinatal period.
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