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| Analysis on vaginal microecology of 174290 women from gynecological clinic |
| National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191 |
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Abstract To analyze the vaginal microecological characteristics of patients from gynecological clinic. Methods: From January 1, 2012 to August 30, 2021, 174,290 patients with symptoms including vulva pruritus, increased leucorrhea, the leucorrhea having unusual smell, or vulva burning or tingling from gynecology outpatients of Peking University Third Hospital were enrolled. The results of vaginal microecology of these patients were analyzed retrospectively. Results: Among 174,290 patients, 45995 (26.4%) patients were diagnosed as vaginitis, which included 23 332 (13.4%) patients with bacterial vaginitis (BV), 17,753 (10.2%) patients with vulvovaginal candidiasis (VVC)，628 (0.4%) patients with trichomonal vaginitis (TV), 3330 (1.9%) patients with VVC combined with BV, and 952 (0.5%) patients with TV combined with BV. Among the patients without diagnosed vaginitis and with normal vaginal flora, the percentage of normal pH value >4.5 and cleanliness III of the patients were 37.9% and 10.7%. In addition, the percentages of vaginal flora inhibition and pH value >4.5 of the patients without vaginitis and aged in ≥50 years old were significantly higher than those of the patients aged in <50 years old, while the percentage of vaginal cleanliness III of the patients without vaginitis and aged in ≥50 years old was significantly lower (all P＜0.05). Conclusion: The patients with different vaginal symptoms from gynecological clinic have different vaginal microecological disorders. The vaginal microecological evaluation system of the patients can guide clinicians to evaluate the vaginal microecological status accurately and comprehensively, so as to reduce the recurrence of vaginal infection repeatedly.
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