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| Correlation between the abnormal thyroid function of pregnant women and their nutrition status, blood lipid level change, and QT interval |
| Minhang Hospital Affiliated to Fudan University, Shanghai, 201100 |
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Abstract To study the correlation between the abnormal thyroid function of pregnant women and their nutrition status, blood lipid level change, and QT interval. Methods: A total of 188 pregnant women with abnormal thyroid function who had been diagnosed and treated were included in this study from January 2020 to December 2020, which included 98 women with hyperthyroidism in group A and 90 women with hypothyroidism in group B. 50 health pregnant women were selected in group C during the same period. The levels of thyroid function indexes, the nutrition status, the blood lipid levels changes, and the QT interval of the women were compared among the three groups. The correlation between the abnormal thyroid function of the women and their nutrition status, blood lipid level change, and QT interval was analyzed. Results: There were significant differences in the serum levels of triiodothyronine (T3), tetraiodothyronine (T4), thyroid stimulating hormone (TSH), total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), total protein (TP), and albumin (ALB), and the QT interval (336.68±12.72 ms vs. 370.25±22.72 ms vs. 368.04±22.26 ms) of the women among the three groups (all P=0.000). Correlation analysis showed that the levels of serum T3, T4 and TSH of the pregnant women with abnormal thyroid function were correlated with their levels of TC, HDL, LDL, TP, and ALB, and their QT interval (all P=0.000). Conclusion: The abnormal thyroid function during pregnancy of the women is significantly correlated with their nutrition indexes, blood lipid level change, and QT interval.
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