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| Observational study on the risk factors of the depression and the pregnancy outcomes of women during pregnancy |
| The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong Province, 510280; 2. Zhuhai District Maternal and Child Health Care Hospital of Guangzhou |
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Abstract To investigate the depression status of women during pregnancy, and to analyze the influencing factors of the depression of these women and the influence on their pregnancy outcomes. Methods: The convenience sampling method was used to select 462 pregnant women who underwent obstetric examination and were divided into group A (women with depression) and group B (women without depression) according to Edinburgh Postnatal Depression Scale (EPDS) from March 1, 2022 to June 30, 2022. The questionnaire was used to collect the basic information of these women, and the possible risk factors of depression of the women were analyzed and screened. The levels of glucose and lipid metabolism indicators of the women were detected, and the adverse pregnancy outcomes of the women were followed up. The correlation between the depression of the women and their adverse pregnancy outcomes was analyzed. Results: The EPDS score of 462 pregnant women was 8.03±4.20 points. There were 155 (33.6%) women in group A (59 cases with moderate to severe depression and 96 cases with mild depression), and there were 307 (66.5%) women in group B. Univariate analysis showed that there were significant differences in the prepregnancy body mass index value, the diet structure, and the rates of unintended pregnancy, history of infertility, less exercise during pregnancy, disharmony relationship with their spouse, and unsatisfied sleep status of the women between group A and group B (P＜0.05). Logistic multifactor regression analysis shows that the history of infertility was not the independent risk factor of depression of the women during pregnancy (P＞0.05), but the high pregnancy body mass index value, the unbalanced diet, the unintended pregnancy, the less exercise during pregnancy, the disharmony relationship with their spouse, the unsatisfied sleep condition were the independent risk factors of depression of the women during pregnancy (P＜0.05). The levels of fasting blood glucose, cholesterol, and triacylglycerol (TG) of the women during the third trimester of pregnancy in group A was no correlated with their depression situation (all P>0.05). The proportions of cesarean section (42.0%) and neonatal hypoglycemia (8.0%) of the women in group A were significantly higher than those (24.5% and 0) of the women in group B (all P＜0.05). Conclusion: The depression during pregnancy of the pregnant women is not conducive to their pregnancy outcomes. It suggests that the risk factors of depression during pregnancy should be paid attention to in clinic, and the targeted intervention should be carried out for reducing the incidence of adverse pregnancy outcomes.
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