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| Effect of laparoscopic improved tubal ampulla fenestration to remove embryo and suture surgery or laparoscopic salpingectomy for treating patients with tubal pregnancy on their ovarian reserve function |
| Zhejiang Chinese Medicine University/Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, Zhejiang Province, 310000 |
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Abstract To investigate the effect of laparoscopic improved tubal abdomen fenestration to remove embryo and suture or laparoscopic salpingectomy for treating patients with tubal ectopic pregnancy on their ovarian reserve function. Methods: The clinical data of 89 patients with tubal ectopic pregnancy from October 2018 to October 2019 were analyzed retrospectively. According to the different surgical methods, these patients were divided into control group (44 patients accepted laparoscopic salpingectomy) and observation group (45 patients accepted laparoscopic improved tubal abdomen fenestration to remove embryo and suture). The serum hormone level, surgical-related indicators, ovarian reserve function, and pregnancy within 2 years after surgery of the patients were compared between the two groups. Results: The operation time (61.8±6.5min) of the patients in the observation group was significant longer than that (54.9±5.3min) of the patients in the control group (P<0.05). There were no significant differences in the intraoperative blood loss, time of getting out of bed, time of hospital stay, and the rate of repetitive ectopic pregnancy within 2 years after operation of the patients between the two groups (P>0.05). At hospital discharge and 6 months after hospital discharge, the levels of FSH, estradiol, and AMT of the patients in the observation group were significant lower than those of the patients in the control group, but the level of luteinizing hormone of the patients in the observation group was significant higher (P<0.05). There was no significant difference in the AFC of the ovary in the same side of tubal ectopic pregnancy at hospital discharge, and in the AFC of the ovary in the other side of tubal ectopic pregnancy at hospital discharge and 6 months after hospital discharge of the patients between the two groups (P>0.05). The AFC (5.9±1.7) of the ovary in the same side of tubal ectopic pregnancy of the patients in the observation group 6 months after hospital discharge was significant higher than that (3.5±1.5) of the patients in the control group. 2 years after operation, the rate of intrauterine pregnancy (75.6%) of the patients in the observation group was significant higher than that (64.6%) of the patients in the control group (P<0.05). Conclusion: Laparoscopic laparoscopic improved tubal abdomen fenestration to remove embryo and suture surgery has less influence on patients' ovarian reserve function than laparoscopic alpingectomy, which can reduce iatrogenic ovarian function damage.
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