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| The clinical therapeutic effects of Tiaojing zhongzi yangmo prescription combined with micro-stimulation plan for treating infertility women with hyporesponsive ovarian |
| Hebi People's Hospital，Henan Province, 458030 |
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Abstract To explore the clinical therapeutic effects of Tiaojing zhongzi yangmo prescription combined with micro-stimulation plan for treating infertility women with hyporesponsive ovarian. Methods: From February 2019 to October 2019, 86 infertility women with hyporesponsive ovarian were divided into two groups (43 cases in each group) by the envelope sealed method. The women in study group were given Tiaojing zhongzi yangmo prescription combined with microstimulation plan, and the women in control group were given micro-stimulation plan only. The changes of sex hormone level before and after treatment, the number of eggs obtained, the endometrium thickness on ET day, the number of MⅡ egg, the fertilization rate of MⅡ egg, the high quality embryo rate, and the pregnancy rate of the women were compared between the two groups. Results: The levels of serum follicle stimulating hormone, luteinizing hormone, and estradiol of the women in both groups had decreased significantly after treatment, and which of the women in the study group were significant lower than those of the women in the control group (P<0.05). The number of eggs obtained (3.2±0.5), the endometrium thickness on ET day (7.8±2.5mm), the number of MⅡeggs (3.0±0.3), the fertilization rate of MⅡ eggs (98.7±3.7%), the quality embryo rate (78.7±2.8%), and the number of quality embryo (2.0±0.2) of the women in the study group were all significant higher than those of the women in the control group (P>0.05). There were no significant differences in the biochemical pregnancy rate, the cycle cancellation rate, the fertilization rate of MⅡ eggs, the estradiol level on HCG day, the Gn dosage, the days of Gn used, and the clinical pregnancy rate of the women between the two groups (P>0.05). Conclusion: Tiaojing zhongzi yangmo prescription combined with micro-stimulation plan for treating infertility women with hyporesponsive ovarian can improve their level of sex hormones, increase the endometrial thickness, and the high quality embryo rate, which contribute to the increase of pregnancy rate.
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