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| The association between the subchorionic hematoma of the pregnant women and their increased risk of preterm birth: a meta-analysis |
| The Obstetrics and Gynecology Hospital Affiliated to Hebei Medical University, Shijiazhuang, Hebei Province, 050000 |
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Abstract To systematically evaluate the association between the subchorionic hematoma (SCH) of the pregnant women and their risk of preterm birth. Methods: The systematically evaluating results were described as odds ratio (OR) and its 95% confidence intervals (CI). The I2 index was used for heterogeneity analysis. Results: A total of 22 literatures were included in the quantitative analysis (3845 women with SCH, and 69,111 women without SCH). The preterm birth risk of the women with SCH were significant higher than those of the women without SCH (OR=1.43, 95% CI 1.28-1.60，P<0.00001; I2=0%). Subgroup analysis showed that this association was not significant when all the women after assisted reproduction (OR=1.38，95 %CI 0.98-1.94，P=0.07; I2=0%). Conclusion: SCH occurrence of the pregnant women is associated with their increased risk of preterm birth, but this association between SCH of the pregnant women after assisted reproduction and their risk of preterm birth is not significant.
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