Abstract To analyze the efficacy of uterine artery embolization for treating patients with uterine scar pregnancy, and to study its influence on their ovarian reserve function and pregnancy outcomes. Methods: The clinical data of 57 patients with uterine scar pregnancy from January 2017 to January 2018 were collected retrospectively. According to different treatment methods, these patients were divided into divided into control group (26 cases with curettage) and observation group (31 cases with uterine artery embolization). The clinical efficacy, ovarian reserve function, prognosis, pregnancy outcomes, and complications rate of the patients after treatment were compared between the two groups. Results: The total effective rate (90.3%) of the patients in the observation group was significant higher than that (65.4%) of the patients in the control group (P<0.05). After treatment, the levels of follicle stimulating hormone (FSH), estradiol (E2), and luteinizing hormone (LH) of the patients in both groups had increased significantly, while antral follicle count (AFC) and LH level of the patients in both groups had decreased significantly, and the changes of which of the patients in the control group were significant more than those of the patients in the observation group (P<0.05). There were no significant differences in menstrual cycle time and menstrual period of the patients after treatment between the two groups (P>0.05). The menstrual recovery time and β-hCG level recovery time of the patients in the observation group were significant shorter than those of the patients in the control group (P<0.05). There were 12 (46.2%) cases with pregnancy in the control group, which included 4 (33.3%) cases with normal pregnancy, and 8 (66.7%) cases with adverse pregnancy. There were 24 (77.4%) cases with pregnancy in the observation group, which included 21 (87.5%) cases with normal pregnancy, and 3 (12.5%) cases with adverse pregnancy. The pregnancy rate and normal pregnancy rate of the patients in the observation group were significant higher than those of the patients in the control group, but the adverse pregnancy rate of the patients in the observation group was significant lower (all P<0.05). The total incidence of complications (9.7%) of the patients in the observation group was significant lower than that (30.8%) of the patients in the control group (P<0.05). Conclusion: Uterine artery embolization treatment can improve the clinical efficacy of patients with uterine scar pregnancy, which has little effect on their ovarian saving function, and can preserve the their fertility function to the greatest extent with good prognosis and high safety.
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